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OLIG1 oligodendrocyte transcription factor 1 [ Homo sapiens (human) ]

Gene ID: 116448, updated on 1-Jun-2020

Summary

Official Symbol
OLIG1provided by HGNC
Official Full Name
oligodendrocyte transcription factor 1provided by HGNC
Primary source
HGNC:HGNC:16983
See related
Ensembl:ENSG00000184221 MIM:606385
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BHLHB6; BHLHE21
Orthologs

Genomic context

See OLIG1 in Genome Data Viewer
Location:
21q22.11
Exon count:
1
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 21 NC_000021.9 (33070141..33072413)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (34442450..34444728)

Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105372785 Neighboring gene long intergenic non-protein coding RNA 945 Neighboring gene VISTA enhancer hs1346 Neighboring gene uncharacterized LOC101928107

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity, RNA polymerase II-specific ISA
Inferred from Sequence Alignment
more info
 
DNA-binding transcription factor activity, RNA polymerase II-specific ISM
Inferred from Sequence Model
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
neuron fate commitment IEA
Inferred from Electronic Annotation
more info
 
oligodendrocyte development IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nuclear chromatin ISA
Inferred from Sequence Alignment
more info
 

General protein information

Preferred Names
oligodendrocyte transcription factor 1
Names
basic domain, helix-loop-helix protein, class B, 6
class B basic helix-loop-helix protein 6
class E basic helix-loop-helix protein 21
oligo1
oligodendrocyte lineage transcription factor 1
oligodendrocyte-specific bHLH transcription factor 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138983.3NP_620450.2  oligodendrocyte transcription factor 1

    See identical proteins and their annotated locations for NP_620450.2

    Status: VALIDATED

    Source sequence(s)
    AL355743, AL834450, AP000289, BC033290
    Consensus CDS
    CCDS42920.2
    UniProtKB/Swiss-Prot
    Q8TAK6
    Related
    ENSP00000371785.1, ENST00000382348.2
    Conserved Domains (1) summary
    pfam00010
    Location:107164
    HLH; Helix-loop-helix DNA-binding domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000021.9 Reference GRCh38.p13 Primary Assembly

    Range
    33070141..33072413
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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