Format

Send to:

Choose Destination

ZNF526 zinc finger protein 526 [ Homo sapiens (human) ]

Gene ID: 116115, updated on 11-Jun-2021

Summary

Official Symbol
ZNF526provided by HGNC
Official Full Name
zinc finger protein 526provided by HGNC
Primary source
HGNC:HGNC:29415
See related
Ensembl:ENSG00000167625 MIM:614387
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in ovary (RPKM 3.0), testis (RPKM 2.9) and 25 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See ZNF526 in Genome Data Viewer
Location:
19q13.2
Exon count:
3
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (42220312..42228201)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (42724464..42732353)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene POU class 2 homeobox 2 Neighboring gene POU2F2 antisense RNA 1 Neighboring gene microRNA 4323 Neighboring gene death effector domain containing 2 Neighboring gene glycogen synthase kinase 3 alpha Neighboring gene ETS2 repressor factor

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC4267, KIAA1951, DKFZp762O059

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_053183.1 RefSeqGene

    Range
    5042..12931
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001314033.3NP_001300962.1  zinc finger protein 526

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AC006486, BC013013, DA236474, DA762298, JQ313906
    Consensus CDS
    CCDS12598.1
    UniProtKB/Swiss-Prot
    Q8TF50
    UniProtKB/TrEMBL
    H9ZYJ3
    Conserved Domains (3) summary
    COG5048
    Location:441550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:474494
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:486511
    zf-H2C2_2; Zinc-finger double domain
  2. NM_133444.3NP_597701.1  zinc finger protein 526

    See identical proteins and their annotated locations for NP_597701.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    AC006486, BC013013, DA762298, JQ313906
    Consensus CDS
    CCDS12598.1
    UniProtKB/Swiss-Prot
    Q8TF50
    UniProtKB/TrEMBL
    H9ZYJ3
    Related
    ENSP00000301215.2, ENST00000301215.8
    Conserved Domains (3) summary
    COG5048
    Location:441550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:474494
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:486511
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    42220312..42228201
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center