Format

Send to:

Choose Destination

LYSMD3 LysM domain containing 3 [ Homo sapiens (human) ]

Gene ID: 116068, updated on 1-Jun-2020

Summary

Official Symbol
LYSMD3provided by HGNC
Official Full Name
LysM domain containing 3provided by HGNC
Primary source
HGNC:HGNC:26969
See related
Ensembl:ENSG00000176018
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in thyroid (RPKM 11.6), adrenal (RPKM 8.4) and 25 other tissues See more
Orthologs

Genomic context

See LYSMD3 in Genome Data Viewer
Location:
5q14.3
Exon count:
3
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (90515626..90529616, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (89811443..89825401, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC731157 Neighboring gene metallo-beta-lactamase domain containing 2 Neighboring gene RNA polymerase III subunit G Neighboring gene adhesion G protein-coupled receptor V1 Neighboring gene uncharacterized LOC105379077 Neighboring gene transmembrane protein 251 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • FLJ13542, DKFZp686F0735

Gene Ontology Provided by GOA

Process Evidence Code Pubs
Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Golgi organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Golgi apparatus IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
lysM and putative peptidoglycan-binding domain-containing protein 3
Names
LysM, putative peptidoglycan-binding, domain containing 3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001286812.1NP_001273741.1  lysM and putative peptidoglycan-binding domain-containing protein 3 isoform 2

    See identical proteins and their annotated locations for NP_001273741.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. It encodes isoform 2, which has a shorter and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC027323, BC058027, BP873090
    Consensus CDS
    CCDS68911.1
    UniProtKB/Swiss-Prot
    Q7Z3D4
    Related
    ENSP00000427683.1, ENST00000509384.5
  2. NM_198273.2NP_938014.1  lysM and putative peptidoglycan-binding domain-containing protein 3 isoform 1

    See identical proteins and their annotated locations for NP_938014.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AL832721, BC136741, CR933624, DN994993
    Consensus CDS
    CCDS43338.1
    UniProtKB/Swiss-Prot
    Q7Z3D4
    UniProtKB/TrEMBL
    A8K613
    Related
    ENSP00000314518.6, ENST00000315948.11
    Conserved Domains (1) summary
    cd00118
    Location:69109
    LysM; Lysine Motif is a small domain involved in binding peptidoglycan

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    90515626..90529616 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005248421.4XP_005248478.1  lysM and putative peptidoglycan-binding domain-containing protein 3 isoform X1

    See identical proteins and their annotated locations for XP_005248478.1

    UniProtKB/Swiss-Prot
    Q7Z3D4
    UniProtKB/TrEMBL
    A8K613
    Conserved Domains (1) summary
    cd00118
    Location:69109
    LysM; Lysine Motif is a small domain involved in binding peptidoglycan
Support Center