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IQCD IQ motif containing D [ Homo sapiens (human) ]

Gene ID: 115811, updated on 23-Nov-2021

Summary

Official Symbol
IQCDprovided by HGNC
Official Full Name
IQ motif containing Dprovided by HGNC
Primary source
HGNC:HGNC:25168
See related
Ensembl:ENSG00000166578
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DRC10; CFAP84; 4933433C09Rik
Expression
Biased expression in testis (RPKM 11.7), lung (RPKM 0.8) and 1 other tissue See more
Orthologs
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Genomic context

See IQCD in Genome Data Viewer
Location:
12q24.13
Exon count:
7
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (113195441..113221341, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (113633251..113658899, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene cilia and flagella associated protein 73 Neighboring gene microRNA 7106 Neighboring gene DEAD-box helicase 54 Neighboring gene RBPJ interacting and tubulin associated 1 Neighboring gene two pore segment channel 1 Neighboring gene uncharacterized LOC107984436 Neighboring gene microRNA 6762

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in ciliary basal body IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in motile cilium IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
dynein regulatory complex protein 10
Names
IQ domain-containing protein D
dynein regulatory complex subunit 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001330452.2NP_001317381.1  dynein regulatory complex protein 10 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC089999, AI638678, AK127152, BC013151, CD358970
    Consensus CDS
    CCDS81743.1
    UniProtKB/Swiss-Prot
    Q96DY2
    Related
    ENSP00000400669.2, ENST00000416617.3
    Conserved Domains (1) summary
    COG1196
    Location:212396
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  2. NM_138451.3NP_612460.1  dynein regulatory complex protein 10 isoform 2

    See identical proteins and their annotated locations for NP_612460.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks two consecutive exons in the 3' coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter but has the same N- and C-termini as isoform 1.
    Source sequence(s)
    AK127152, BC013151
    Consensus CDS
    CCDS9167.1
    UniProtKB/Swiss-Prot
    Q96DY2
    UniProtKB/TrEMBL
    A0A024RBQ9
    Related
    ENSP00000299732.2, ENST00000299732.6
    Conserved Domains (1) summary
    cl25732
    Location:101297
    SMC_N; RecF/RecN/SMC N terminal domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    113195441..113221341 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011537864.2XP_011536166.1  dynein regulatory complex protein 10 isoform X2

    Conserved Domains (1) summary
    TIGR02168
    Location:101319
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  2. XM_005253834.4XP_005253891.1  dynein regulatory complex protein 10 isoform X3

    Conserved Domains (1) summary
    COG1196
    Location:56215
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  3. XM_005253833.4XP_005253890.1  dynein regulatory complex protein 10 isoform X1

    See identical proteins and their annotated locations for XP_005253890.1

    UniProtKB/Swiss-Prot
    Q96DY2
    Conserved Domains (1) summary
    COG1196
    Location:212396
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  4. XM_011537863.2XP_011536165.1  dynein regulatory complex protein 10 isoform X1

    See identical proteins and their annotated locations for XP_011536165.1

    UniProtKB/Swiss-Prot
    Q96DY2
    Conserved Domains (1) summary
    COG1196
    Location:212396
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
  5. XM_011537862.2XP_011536164.1  dynein regulatory complex protein 10 isoform X1

    See identical proteins and their annotated locations for XP_011536164.1

    UniProtKB/Swiss-Prot
    Q96DY2
    Conserved Domains (1) summary
    COG1196
    Location:212396
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
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