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Adss adenylosuccinate synthetase, non muscle [ Mus musculus (house mouse) ]

Gene ID: 11566, updated on 31-Jan-2019

Summary

Official Symbol
Adssprovided by MGI
Official Full Name
adenylosuccinate synthetase, non muscleprovided by MGI
Primary source
MGI:MGI:87948
See related
Ensembl:ENSMUSG00000015961
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AS; Adss2; AI314886
Expression
Ubiquitous expression in CNS E18 (RPKM 16.5), CNS E14 (RPKM 15.7) and 28 other tissues See more
Orthologs

Genomic context

See Adss in Genome Data Viewer
Location:
1; 1 H4
Exon count:
13
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (177763176..177796695, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (179693309..179726640, complement)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2310043L19 gene Neighboring gene RIKEN cDNA 1700016C15 gene Neighboring gene predicted gene, 30115 Neighboring gene ribosomal protein S8 pseudogene Neighboring gene cation channel sperm associated auxiliary subunit epsilon 1 Neighboring gene cation channel sperm associated auxiliary subunit epsilon 2 Neighboring gene translin-associated factor X pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
GTP binding IEA
Inferred from Electronic Annotation
more info
 
adenylosuccinate synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
adenylosuccinate synthase activity IDA
Inferred from Direct Assay
more info
PubMed 
adenylosuccinate synthase activity ISO
Inferred from Sequence Orthology
more info
 
ligase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
'de novo' AMP biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
AMP biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
AMP biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
IMP metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
IMP metabolic process ISO
Inferred from Sequence Orthology
more info
 
aspartate metabolic process ISO
Inferred from Sequence Orthology
more info
 
purine nucleotide biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol ISO
Inferred from Sequence Orthology
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
adenylosuccinate synthetase isozyme 2
Names
AMPSase 2
IMP--aspartate ligase 2
L-type adenylosuccinate synthetase
adSS 2
adenylosuccinate synthetase 2, non muscle
adenylosuccinate synthetase, acidic isozyme
adenylosuccinate synthetase, liver isozyme
adenylosuccinate synthetase, non-muscle isozyme
NP_031448.2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007422.3NP_031448.2  adenylosuccinate synthetase isozyme 2

    See identical proteins and their annotated locations for NP_031448.2

    Status: VALIDATED

    Source sequence(s)
    AK028060
    Consensus CDS
    CCDS15555.1
    UniProtKB/Swiss-Prot
    P46664
    UniProtKB/TrEMBL
    B9EIE9
    Related
    ENSMUSP00000016105.8, ENSMUST00000016105.8
    Conserved Domains (1) summary
    pfam00709
    Location:32453
    Adenylsucc_synt; Adenylosuccinate synthetase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

    Range
    177763176..177796695 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_001785476.1 RNA Sequence

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