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ZNF689 zinc finger protein 689 [ Homo sapiens (human) ]

Gene ID: 115509, updated on 1-Jun-2020

Summary

Official Symbol
ZNF689provided by HGNC
Official Full Name
zinc finger protein 689provided by HGNC
Primary source
HGNC:HGNC:25173
See related
Ensembl:ENSG00000156853 MIM:618033
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TIPUH1
Expression
Broad expression in testis (RPKM 14.6), ovary (RPKM 2.9) and 24 other tissues See more
Orthologs

Genomic context

See ZNF689 in Genome Data Viewer
Location:
16p11.2
Exon count:
5
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (30602558..30610775, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (30613879..30622096, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 688 Neighboring gene zinc finger protein 785 Neighboring gene proline rich 14 Neighboring gene fibrosin

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ90415, DKFZp762C173

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
skeletal muscle cell differentiation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein 689
Names
transcription-involved protein upregulated in HCC 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138447.3NP_612456.1  zinc finger protein 689

    See identical proteins and their annotated locations for NP_612456.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the functional protein.
    Source sequence(s)
    AC093249, AL834299, BC014000, DA485303
    Consensus CDS
    CCDS10686.1
    UniProtKB/Swiss-Prot
    Q96CS4
    Related
    ENSP00000287461.3, ENST00000287461.8
    Conserved Domains (3) summary
    smart00349
    Location:2988
    KRAB; krueppel associated box
    COG5048
    Location:159466
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:263283
    ZF_C2H2; C2H2 Zn finger [structural motif]

RNA

  1. NR_073480.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 5' exon, compared to variant 1. This variant is represented as non-coding because it lacks an in-frame ORF, compared to variant 1.
    Source sequence(s)
    AC093249, AK310459, AL834299, DA485303
  2. NR_073481.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' exon, compared to variant 1. This variant is represented as non-coding because it lacks an in-frame ORF, compared to variant 1.
    Source sequence(s)
    AL834299, BC014000, CN406120, DA010230
  3. NR_073482.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' exon, compared to variant 1. This variant is represented as non-coding because it lacks an in-frame ORF, compared to variant 1.
    Source sequence(s)
    AL834299, BC014000, DB456506
  4. NR_104166.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' exon, compared to variant 1. This variant is represented as non-coding because it lacks an in-frame ORF, compared to variant 1.
    Source sequence(s)
    AC093249, AL834299, CD243730, HY005770

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    30602558..30610775 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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