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Gpr182 G protein-coupled receptor 182 [ Mus musculus (house mouse) ]

Gene ID: 11536, updated on 1-Mar-2024

Summary

Official Symbol
Gpr182provided by MGI
Official Full Name
G protein-coupled receptor 182provided by MGI
Primary source
MGI:MGI:109545
See related
Ensembl:ENSMUSG00000058396 AllianceGenome:MGI:109545
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
NOW; AM-R; Admr; MB10; G10-D; Gpcr17; Gpcr22
Summary
Predicted to enable adrenomedullin receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Is expressed in several structures, including central nervous system; gut; heart; reproductive system; and retina. Orthologous to human GPR182 (G protein-coupled receptor 182). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in lung adult (RPKM 41.9), spleen adult (RPKM 27.7) and 12 other tissues See more
Orthologs
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Genomic context

See Gpr182 in Genome Data Viewer
Location:
10 D3; 10 75.07 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (127585471..127587667, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (127749602..127751798, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene tachykinin 2 Neighboring gene zinc finger and BTB domain containing 39 Neighboring gene STARR-seq mESC enhancer starr_28236 Neighboring gene retinol dehydrogenase 1 (all trans) Neighboring gene retinol dehydrogenase 9 Neighboring gene STARR-seq mESC enhancer starr_28237

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables adrenomedullin receptor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
G-protein coupled receptor 182
Names
G10D
adrenomedullin receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007412.2NP_031438.2  G-protein coupled receptor 182

    See identical proteins and their annotated locations for NP_031438.2

    Status: VALIDATED

    Source sequence(s)
    BB806742, BC125279, BY121440, BY590401
    Consensus CDS
    CCDS36084.1
    UniProtKB/Swiss-Prot
    P43142
    UniProtKB/TrEMBL
    G3X9R9
    Related
    ENSMUSP00000100882.3, ENSMUST00000079692.6
    Conserved Domains (1) summary
    cd14988
    Location:50327
    7tmA_GPR182; G protein-coupled receptor 182, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    127585471..127587667 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)