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DDIT4L DNA damage inducible transcript 4 like [ Homo sapiens (human) ]

Gene ID: 115265, updated on 7-Jun-2020

Summary

Official Symbol
DDIT4Lprovided by HGNC
Official Full Name
DNA damage inducible transcript 4 likeprovided by HGNC
Primary source
HGNC:HGNC:30555
See related
Ensembl:ENSG00000145358 MIM:607730
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
REDD2; Rtp801L
Expression
Biased expression in prostate (RPKM 12.6), kidney (RPKM 5.8) and 10 other tissues See more
Orthologs

Genomic context

See DDIT4L in Genome Data Viewer
Location:
4q24
Exon count:
3
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (100185870..100190468, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (101106267..101111939, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene dynein light chain LC8-type 1 pseudogene 6 Neighboring gene uncharacterized LOC107986232 Neighboring gene uncharacterized LOC101929353 Neighboring gene small nucleolar RNA, H/ACA box 101A Neighboring gene endomucin

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
negative regulation of signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
DNA damage-inducible transcript 4-like protein
Names
HIF-1 responsive protein RTP801-like
REDD-2
homolog of mouse SMHS1
protein regulated in development and DNA damage response 2
regulated in development and DNA damage response 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145244.4NP_660287.1  DNA damage-inducible transcript 4-like protein

    See identical proteins and their annotated locations for NP_660287.1

    Status: VALIDATED

    Source sequence(s)
    AK094236, BC013592
    Consensus CDS
    CCDS34036.1
    UniProtKB/Swiss-Prot
    Q96D03
    Related
    ENSP00000354830.2, ENST00000273990.6
    Conserved Domains (1) summary
    pfam07809
    Location:65183
    RTP801_C; RTP801 C-terminal region

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    100185870..100190468 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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