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FLYWCH2 FLYWCH family member 2 [ Homo sapiens (human) ]

Gene ID: 114984, updated on 1-Jun-2020

Summary

Official Symbol
FLYWCH2provided by HGNC
Official Full Name
FLYWCH family member 2provided by HGNC
Primary source
HGNC:HGNC:25178
See related
Ensembl:ENSG00000162076
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in spleen (RPKM 10.8), prostate (RPKM 8.6) and 25 other tissues See more
Orthologs

Genomic context

See FLYWCH2 in Genome Data Viewer
Location:
16p13.3
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (2882804..2899382)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (2932924..2949383)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene serine protease 22 Neighboring gene uncharacterized LOC101929566 Neighboring gene FLYWCH-type zinc finger 1 Neighboring gene ribosomal protein L23a pseudogene 86 Neighboring gene uncharacterized LOC105371055

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001142499.1NP_001135971.1  FLYWCH family member 2

    See identical proteins and their annotated locations for NP_001135971.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All three variants encode the same protein.
    Source sequence(s)
    AL542248, BC014089, BG120460, CA413438, DB455461
    Consensus CDS
    CCDS10482.1
    UniProtKB/Swiss-Prot
    Q96CP2
    Related
    ENSP00000293981.6, ENST00000293981.10
    Conserved Domains (1) summary
    pfam15423
    Location:1106
    FLYWCH_N; FLYWCH-type zinc finger-containing protein
  2. NM_001142500.1NP_001135972.1  FLYWCH family member 2

    See identical proteins and their annotated locations for NP_001135972.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All three variants encode the same protein.
    Source sequence(s)
    BC014089, BG120460, BI825861, CA413438, DB455461
    Consensus CDS
    CCDS10482.1
    UniProtKB/Swiss-Prot
    Q96CP2
    Conserved Domains (1) summary
    pfam15423
    Location:1106
    FLYWCH_N; FLYWCH-type zinc finger-containing protein
  3. NM_138439.3NP_612448.1  FLYWCH family member 2

    See identical proteins and their annotated locations for NP_612448.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. All three variants encode the same protein.
    Source sequence(s)
    BC014089, BG120460, CA413438, DB455461
    Consensus CDS
    CCDS10482.1
    UniProtKB/Swiss-Prot
    Q96CP2
    Related
    ENSP00000380159.3, ENST00000396958.8
    Conserved Domains (1) summary
    pfam15423
    Location:1106
    FLYWCH_N; FLYWCH-type zinc finger-containing protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    2882804..2899382
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005255078.5XP_005255135.1  FLYWCH family member 2 isoform X1

    See identical proteins and their annotated locations for XP_005255135.1

    UniProtKB/Swiss-Prot
    Q96CP2
    Conserved Domains (1) summary
    pfam15423
    Location:1106
    FLYWCH_N; FLYWCH-type zinc finger-containing protein
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