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GPRIN1 G protein regulated inducer of neurite outgrowth 1 [ Homo sapiens (human) ]

Gene ID: 114787, updated on 6-Sep-2022

Summary

Official Symbol
GPRIN1provided by HGNC
Official Full Name
G protein regulated inducer of neurite outgrowth 1provided by HGNC
Primary source
HGNC:HGNC:24835
See related
Ensembl:ENSG00000169258 MIM:611239; AllianceGenome:HGNC:24835
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GRIN1
Summary
Predicted to enable phosphoprotein binding activity. Predicted to be involved in neuron projection development. Predicted to be located in growth cone. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in brain (RPKM 11.5), duodenum (RPKM 2.2) and 5 other tissues See more
Orthologs
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Genomic context

See GPRIN1 in Genome Data Viewer
Location:
5q35.2
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (176595802..176610156, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (177142394..177156751, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (176022803..176037157, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene cadherin related family member 2 Neighboring gene RNA, 7SL, cytoplasmic 684, pseudogene Neighboring gene Sharpr-MPRA regulatory region 7457 Neighboring gene Sharpr-MPRA regulatory region 11151 Neighboring gene synuclein beta Neighboring gene microRNA 4281

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA1893

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables phosphoprotein binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in neuron projection development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in growth cone IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
G protein-regulated inducer of neurite outgrowth 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_052899.3NP_443131.2  G protein-regulated inducer of neurite outgrowth 1

    See identical proteins and their annotated locations for NP_443131.2

    Status: VALIDATED

    Source sequence(s)
    AC091934
    Consensus CDS
    CCDS4405.1
    UniProtKB/Swiss-Prot
    Q7Z2K8, Q96PZ4
    Related
    ENSP00000305839.4, ENST00000303991.5
    Conserved Domains (1) summary
    pfam15235
    Location:8731005
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    176595802..176610156 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    177142394..177156751 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)