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Mllt3 MLLT3, super elongation complex subunit [ Rattus norvegicus (Norway rat) ]

Gene ID: 114510, updated on 18-Apr-2019

Summary

Official Symbol
Mllt3provided by RGD
Official Full Name
MLLT3, super elongation complex subunitprovided by RGD
Primary source
RGD:620940
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Af9; Af-9
Summary
mouse homolog regulates pattern formation during embryogenesis [RGD, Feb 2006]
Annotation information
Annotation category: partial on reference assembly
Expression
Biased expression in Muscle (RPKM 157.5), Thymus (RPKM 100.1) and 9 other tissues See more
Orthologs

Genomic context

See Mllt3 in Genome Data Viewer
Location:
5q32
Exon count:
8
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (106103498..106202559, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 5 NC_005104.3 (110089246..110183694, complement)

Chromosome 5 - NC_005104.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108350994 Neighboring gene uncharacterized LOC108350995 Neighboring gene uncharacterized LOC103692403 Neighboring gene uncharacterized LOC108351134

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
chromatin binding ISO
Inferred from Sequence Orthology
more info
PubMed 
histone binding ISO
Inferred from Sequence Orthology
more info
PubMed 
lysine-acetylated histone binding ISO
Inferred from Sequence Orthology
more info
PubMed 
modification-dependent protein binding ISO
Inferred from Sequence Orthology
more info
PubMed 
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
anterior/posterior pattern specification ISO
Inferred from Sequence Orthology
more info
PubMed 
biological_process ND
No biological Data available
more info
 
negative regulation of canonical Wnt signaling pathway ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of Wnt signaling pathway, planar cell polarity pathway ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
PubMed 
segment specification ISO
Inferred from Sequence Orthology
more info
PubMed 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
transcription elongation factor complex ISO
Inferred from Sequence Orthology
more info
PubMed 

General protein information

Preferred Names
protein AF-9
Names
myeloid/lymphoid or mixed lineage-leukemia translocation to 3 homolog
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
myeloid/lymphoid or mixed-lineage leukemia,translocated to, 3 (trithorax homolog, Drosophila)
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
translocated to, 3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_053718.2NP_446170.1  protein AF-9

    See identical proteins and their annotated locations for NP_446170.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ006295
    UniProtKB/TrEMBL
    O88760

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005104.4 Reference Rnor_6.0 Primary Assembly

    Range
    106103498..106202559 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000073.1 Alternate Rn_Celera

    Range
    100747987..100840556
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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