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H2BK1 H2B.K variant histone 1 [ Homo sapiens (human) ]

Gene ID: 114483833, updated on 13-May-2022

Summary

Official Symbol
H2BK1provided by HGNC
Official Full Name
H2B.K variant histone 1provided by HGNC
Primary source
HGNC:HGNC:53833
See related
Ensembl:ENSG00000285480 AllianceGenome:HGNC:53833
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
H2BE1
Summary
Predicted to enable DNA binding activity. Predicted to be involved in nucleosome assembly. Predicted to be located in nucleus. Predicted to be part of nucleosome. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See H2BK1 in Genome Data Viewer
Location:
7q36.1
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (151207837..151210488, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (152380955..152383602, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (150904923..150907574, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene ankyrin repeat and SOCS box containing 10 Neighboring gene IQ motif containing with AAA domain 1 like Neighboring gene ABCF2-H2BK1 readthrough Neighboring gene ATP binding cassette subfamily F member 2 Neighboring gene chondroitin polymerizing factor 2 Neighboring gene microRNA 671

Genomic regions, transcripts, and products

General gene information

Readthrough ABCF2-H2BK1

Readthrough gene: ABCF2-H2BK1, Included gene: ABCF2

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in nucleosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of nucleosome IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
histone H2B type 2-K1
Names
H2B.E variant histone 1
histone H2B type 2-E1
novel histone H2B-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001369125.3NP_001356054.2  histone H2B type 2-K1

    Status: VALIDATED

    Source sequence(s)
    AC021097
    Related
    ENSP00000495192.1, ENST00000644661.2
    Conserved Domains (1) summary
    smart00427
    Location:32120
    H2B; Histone H2B

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    151207837..151210488 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    152380955..152383602 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)