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sim2 SIM bHLH transcription factor 2 [ Danio rerio (zebrafish) ]

Gene ID: 114450, updated on 3-Oct-2019

Summary

Official Symbol
sim2provided by ZNC
Official Full Name
SIM bHLH transcription factor 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-010803-1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Annotation information
Annotation category: partial on reference assembly
Orthologs

Genomic context

See sim2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
10
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (47035..78538)
106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (8503995..8510201, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (9608..11974)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (8625302..8631508, complement)
103 previous assembly Zv9 (GCF_000002035.4) 10 NC_007121.5 (74411..79104)
103 previous assembly Zv9 (GCF_000002035.4) 3 NC_007114.5 (9087935..9094141, complement)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene tripartite motif containing 35-9 Neighboring gene cytochrome P450, family 2, subfamily k, polypeptide 31 Neighboring gene tripartite motif containing 35-10 Neighboring gene RNA binding fox-1 homolog 3b Neighboring gene E3 ubiquitin-protein ligase rnf213-alpha-like Neighboring gene transfer RNA proline (anticodon UGG)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene TIP41, TOR signaling pathway regulator-like (S. cerevisiae) Neighboring gene ribosomal oxygenase 2 Neighboring gene crystallin beta-gamma domain containing 3 Neighboring gene holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) Neighboring gene dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, a Neighboring gene VPS26 endosomal protein sorting factor C Neighboring gene tetratricopeptide repeat domain 3 Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class P

Genomic regions, transcripts, and products

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
transcription factor complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
single-minded homolog 2
Names
single-minded family bHLH transcription factor 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_131836.1NP_571911.1  single-minded homolog 2

    See identical proteins and their annotated locations for NP_571911.1

    Status: PROVISIONAL

    Source sequence(s)
    AF363019
    UniProtKB/TrEMBL
    Q8UVV3
    Conserved Domains (5) summary
    cd00083
    Location:252
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cd00130
    Location:88158
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam00989
    Location:82143
    PAS; PAS fold
    pfam06621
    Location:359578
    SIM_C; Single-minded protein C-terminus
    pfam08447
    Location:240326
    PAS_3; PAS fold

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    8503995..8510201 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    47035..78538
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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