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pola1 polymerase (DNA directed), alpha 1 [ Xiphophorus couchianus (Monterrey platyfish) ]

Gene ID: 114137039, updated on 15-Mar-2024

Summary

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Gene symbol
pola1
Gene description
polymerase (DNA directed), alpha 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Xiphophorus couchianus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; Xiphophorus
Orthologs
human zebrafish all
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Genomic context

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See pola1 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
37
Annotation release Status Assembly Chr Location
101 current X_couchianus-1.0 (GCF_001444195.1) 21 NC_040248.1 (13888552..13944817)

Chromosome 21 - NC_040248.1Genomic Context describing neighboring genes Neighboring gene pyruvate dehydrogenase kinase, isozyme 3a Neighboring gene phosphate cytidylyltransferase 1, choline, beta Neighboring gene aristaless related homeobox a Neighboring gene homogentisate 1,2-dioxygenase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_040248.1 Chromosome 21 Reference X_couchianus-1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA replication origin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA-directed DNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables purine nucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyrimidine nucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lagging strand elongation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in leading strand elongation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic DNA replication initiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of alpha DNA polymerase:primase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA polymerase alpha catalytic subunit
Names
DNA polymerase alpha 1, catalytic subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xiphophorus couchianus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference X_couchianus-1.0 Primary Assembly

Genomic

  1. NC_040248.1 Reference X_couchianus-1.0 Primary Assembly

    Range
    13888552..13944817
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028005533.1 → XP_027861334.1  DNA polymerase alpha catalytic subunit isoform X1

    UniProtKB/TrEMBL
    A0A3B5LDF7
    Conserved Domains (2) summary
    TIGR00592
    Location:59 → 1242
    pol2; DNA polymerase (pol2)
    pfam08996
    Location:1283 → 1470
    zf-DNA_Pol; DNA Polymerase alpha zinc finger

  2. XM_028005534.1 → XP_027861335.1  DNA polymerase alpha catalytic subunit isoform X2

    UniProtKB/TrEMBL
    A0A3B5LDF7
    Conserved Domains (2) summary
    TIGR00592
    Location:59 → 1241
    pol2; DNA polymerase (pol2)
    pfam08996
    Location:1282 → 1469
    zf-DNA_Pol; DNA Polymerase alpha zinc finger
Nucleotide Protein
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