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ATF7-NPFF ATF7-NPFF readthrough [ Homo sapiens (human) ]

Gene ID: 114108587, updated on 5-Jan-2022

Summary

Official Symbol
ATF7-NPFFprovided by HGNC
Official Full Name
ATF7-NPFF readthroughprovided by HGNC
Primary source
HGNC:HGNC:55073
See related
Ensembl:ENSG00000267281
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable DNA binding activity and DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Nov 2021]
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Genomic context

See ATF7-NPFF in Genome Data Viewer
Location:
12q13.13
Exon count:
15
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (53506688..53626382, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (53900472..54020166, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene poly(rC) binding protein 2 Neighboring gene PCBP2 overlapping transcript 1 Neighboring gene mitogen-activated protein kinase kinase kinase 12 Neighboring gene Sharpr-MPRA regulatory region 3466 Neighboring gene uncharacterized LOC100652999 Neighboring gene TARBP2 subunit of RISC loading complex Neighboring gene neuropeptide FF-amide peptide precursor Neighboring gene activating transcription factor 7 Neighboring gene zinc finger protein 337 pseudogene Neighboring gene Sharpr-MPRA regulatory region 12722 Neighboring gene ribosomal protein L31 pseudogene 51

Genomic regions, transcripts, and products

General protein information

Preferred Names
ATF7-NPFF readthrough protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001366559.1NP_001353488.1  ATF7-NPFF readthrough protein isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC023509, AC073594
    Related
    ENSP00000466174.1, ENST00000591834.1
    Conserved Domains (4) summary
    cd12192
    Location:4784
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    cd14687
    Location:334394
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    sd00019
    Location:931
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:731
    zf-C2H2; Zinc finger, C2H2 type
  2. NM_001366560.1NP_001353489.1  ATF7-NPFF readthrough protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC023509, AC073594
    Conserved Domains (4) summary
    cd12192
    Location:4784
    GCN4_cent; GCN4 central activation domain-like acidic activation domain
    cd14687
    Location:334394
    bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
    sd00019
    Location:931
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:731
    zf-C2H2; Zinc finger, C2H2 type

RNA

  1. NR_159377.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC023509, AC073594

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    53506688..53626382 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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