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Sbk1 SH3 domain binding kinase 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 113907, updated on 25-Nov-2021

Summary

Symbol
Sbk1provided by RGD
Full Name
SH3 domain binding kinase 1provided by RGD
Primary source
RGD:628713
See related
EnsemblRapid:ENSRNOG00000067387
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Sbk
Summary
serine/threonine protein kinase gene expressed predominantly in developing brain [RGD, Feb 2006]
Expression
Biased expression in Adrenal (RPKM 247.9), Thymus (RPKM 95.7) and 7 other tissues See more
Orthologs
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Genomic context

See Sbk1 in Genome Data Viewer
Location:
1q36
Exon count:
5
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (180807092..180851910)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (197636230..197681031)

Chromosome 1 - NC_051336.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108349639 Neighboring gene uncharacterized LOC120099931 Neighboring gene uncharacterized LOC108349640 Neighboring gene uncharacterized LOC102548820 Neighboring gene linker for activation of T cells

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables protein serine kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein serine/threonine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein serine/threonine/tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in brain development IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in peptidyl-serine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in peptidyl-serine phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in peptidyl-threonine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in peptidyl-threonine phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
serine/threonine-protein kinase SBK1
Names
SH3-binding domain kinase 1
SH3-binding kinase 1
NP_671476.1
XP_017444131.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_147135.3NP_671476.1  serine/threonine-protein kinase SBK1

    See identical proteins and their annotated locations for NP_671476.1

    Status: PROVISIONAL

    Source sequence(s)
    JACYVU010000044
    UniProtKB/Swiss-Prot
    Q9Z335
    Related
    ENSRNOP00000073472.1, ENSRNOT00000082228.2
    Conserved Domains (2) summary
    smart00220
    Location:53316
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd13987
    Location:59317
    STKc_SBK1; Catalytic domain of the Serine/Threonine kinase, SH3 Binding Kinase 1

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051336.1 Reference mRatBN7.2 Primary Assembly

    Range
    180807092..180851910
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017588642.2XP_017444131.1  serine/threonine-protein kinase SBK1 isoform X1

    UniProtKB/Swiss-Prot
    Q9Z335
    Related
    ENSRNOP00000025808.4, ENSRNOT00000025808.6
    Conserved Domains (2) summary
    smart00220
    Location:53316
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd13987
    Location:59317
    STKc_SBK1; Catalytic domain of the Serine/Threonine kinase, SH3 Binding Kinase 1
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