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FAM83F family with sequence similarity 83 member F [ Homo sapiens (human) ]

Gene ID: 113828, updated on 11-Jun-2025
Official Symbol
FAM83Fprovided by HGNC
Official Full Name
family with sequence similarity 83 member Fprovided by HGNC
Primary source
HGNC:HGNC:25148
See related
Ensembl:ENSG00000133477 AllianceGenome:HGNC:25148
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable protein kinase binding activity. Predicted to be involved in signal transduction. [provided by Alliance of Genome Resources, Jun 2025]
Expression
Biased expression in testis (RPKM 11.4), skin (RPKM 5.5) and 12 other tissues See more
Orthologs
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See FAM83F in Genome Data Viewer
Location:
22q13.1
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (39994954..40043534)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (40465916..40515097)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (40390958..40439538)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene GRB2 related adaptor protein 2 Neighboring gene ReSE screen-validated silencer GRCh37_chr22:40361232-40361409 Neighboring gene uncharacterized LOC124905155 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:40390673-40391306 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr22:40393419-40394024 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr22:40394025-40394630 Neighboring gene translation machinery associated 7 homolog B Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:40401347-40401848 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:40401849-40402348 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:40418684-40419184 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:40419185-40419685 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19079 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:40426725-40427244 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:40439529-40440176 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19080 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19081 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13766 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13767 Neighboring gene ReSE screen-validated silencer GRCh37_chr22:40442874-40443092 Neighboring gene TNRC6B divergent transcript Neighboring gene trinucleotide repeat containing adaptor 6B Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr22:40497428-40497948 Neighboring gene ribosomal protein L7 pseudogene 52 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19082 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:40591286-40591820 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:40591821-40592353 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19083 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:40624195-40624696 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:40633809-40634710 Neighboring gene uncharacterized LOC124905121

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
Products Interactant Other Gene Complex Source Pubs Description

Markers

Clone Names

  • FLJ44317

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
protein FAM83F

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138435.4NP_612444.2  protein FAM83F

    See identical proteins and their annotated locations for NP_612444.2

    Status: VALIDATED

    Source sequence(s)
    KF457465, Z82206, Z83847
    Consensus CDS
    CCDS14000.2
    UniProtKB/Swiss-Prot
    Q8NEG4, Q96FD6
    Related
    ENSP00000330432.5, ENST00000333407.11
    Conserved Domains (2) summary
    cd09186
    Location:20295
    PLDc_FAM83F_N; N-terminal phospholipase D-like domain of the uncharacterized protein, Family with sequence similarity 83F
    pfam13091
    Location:154291
    PLDc_2; PLD-like domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    39994954..40043534
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    40465916..40515097
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_039988.1: Suppressed sequence

    Description
    NR_039988.1: This RefSeq was removed because the gene was discontinued.