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LOC113748408 Sharpr-MPRA regulatory region 8580 [ Homo sapiens (human) ]

Gene ID: 113748408, updated on 12-Oct-2019

Summary

Gene symbol
LOC113748408
Gene description
Sharpr-MPRA regulatory region 8580
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence was predicted to be a transcriptional regulatory region based on chromatin state analysis from the ENCODE (ENCyclopedia Of DNA Elements) project. It was validated as a functional enhancer by the Sharpr-MPRA technique (Systematic high-resolution activation and repression profiling with reporter tiling using massively parallel reporter assays) in both HepG2 liver carcinoma cells (group: HepG2 Activating DNase unmatched - State 12:CtcfO, distal CTCF/candidate insulator with open chromatin) and K562 erythroleukemia cells (group: K562 Activating DNase unmatched - State 25:Art, potential CNV or repetitive artifacts). [provided by RefSeq, Dec 2018]

Genomic context

See LOC113748408 in Genome Data Viewer
Location:
7q
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (73734759..73735053)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene syntaxin 1A Neighboring gene microRNA 4284 Neighboring gene RNA, 7SL, cytoplasmic 265, pseudogene Neighboring gene ABHD11 antisense RNA 1 (tail to tail) Neighboring gene abhydrolase domain containing 11

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_062519.1 

    Range
    101..395
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    73734759..73735053
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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