Format

Send to:

Choose Destination

RPUSD1 RNA pseudouridine synthase domain containing 1 [ Homo sapiens (human) ]

Gene ID: 113000, updated on 23-Nov-2021

Summary

Official Symbol
RPUSD1provided by HGNC
Official Full Name
RNA pseudouridine synthase domain containing 1provided by HGNC
Primary source
HGNC:HGNC:14173
See related
Ensembl:ENSG00000007376
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RLUCL; C16orf40
Expression
Ubiquitous expression in spleen (RPKM 5.2), colon (RPKM 4.3) and 25 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See RPUSD1 in Genome Data Viewer
Location:
16p13.3
Exon count:
6
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (784974..788381, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (834974..838381, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene MSLN promoter region Neighboring gene mesothelin Neighboring gene mesothelin like Neighboring gene microRNA 662 Neighboring gene chromosome transmission fidelity factor 18 Neighboring gene G protein subunit gamma 13 Neighboring gene proline rich 25

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC19600

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables pseudouridine synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in enzyme-directed rRNA pseudouridine synthesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
RNA pseudouridylate synthase domain-containing protein 1
Names
RNA pseudouridylate synthase domain containing 1
ribosomal large subunit pseudouridine synthase C-like protein

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_047098.1 RefSeqGene

    Range
    5007..8414
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001324086.2NP_001311015.1  RNA pseudouridylate synthase domain-containing protein 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL031033
    Conserved Domains (2) summary
    cd02869
    Location:18218
    PseudoU_synth_RluCD_like; Pseudouridine synthase, RsuA/RluD family
    COG0564
    Location:9233
    RluA; Pseudouridylate synthase, 23S rRNA- or tRNA-specific [Translation, ribosomal structure and biogenesis]
  2. NM_001324410.2NP_001311339.1  RNA pseudouridylate synthase domain-containing protein 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL031033, AL514840
    Related
    ENSP00000454616.1, ENST00000569601.5
    Conserved Domains (1) summary
    cd02869
    Location:989
    PseudoU_synth_RluCD_like; Pseudouridine synthase, RsuA/RluD family
  3. NM_001324411.2NP_001311340.1  RNA pseudouridylate synthase domain-containing protein 1 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL031033, AL520203
    Consensus CDS
    CCDS81924.1
    UniProtKB/TrEMBL
    H3BUN6
    Related
    ENSP00000457722.1, ENST00000565809.5
    Conserved Domains (1) summary
    cd02869
    Location:18103
    PseudoU_synth_RluCD_like; Pseudouridine synthase, RsuA/RluD family
  4. NM_001324412.2NP_001311341.1  RNA pseudouridylate synthase domain-containing protein 1 isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5), as well as variants 6, 7, and 8, encodes isoform 5.
    Source sequence(s)
    AL031033, BX358716
    Consensus CDS
    CCDS81923.1
    UniProtKB/TrEMBL
    H3BQN8
    Related
    ENSP00000455862.1, ENST00000567114.5
    Conserved Domains (1) summary
    cd02869
    Location:886
    PseudoU_synth_RluCD_like; Pseudouridine synthase, RsuA/RluD family
  5. NM_001324413.2NP_001311342.1  RNA pseudouridylate synthase domain-containing protein 1 isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6), as well as variants 5, 7, and 8, encodes isoform 5.
    Source sequence(s)
    AL031033, CN311779
    Consensus CDS
    CCDS81923.1
    UniProtKB/TrEMBL
    H3BQN8
    Related
    ENSP00000456692.1, ENST00000565377.1
    Conserved Domains (1) summary
    cd02869
    Location:886
    PseudoU_synth_RluCD_like; Pseudouridine synthase, RsuA/RluD family
  6. NM_001324414.2NP_001311343.1  RNA pseudouridylate synthase domain-containing protein 1 isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7), as well as variants 5, 6, and 8, encodes isoform 5.
    Source sequence(s)
    AL031033, CN311777
    Consensus CDS
    CCDS81923.1
    UniProtKB/TrEMBL
    H3BQN8
    Conserved Domains (1) summary
    cd02869
    Location:886
    PseudoU_synth_RluCD_like; Pseudouridine synthase, RsuA/RluD family
  7. NM_001324415.2NP_001311344.1  RNA pseudouridylate synthase domain-containing protein 1 isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8), as well as variants 5, 6, and 7, encodes isoform 5.
    Source sequence(s)
    AL031033, CX786721
    Consensus CDS
    CCDS81923.1
    UniProtKB/TrEMBL
    H3BQN8
    Conserved Domains (1) summary
    cd02869
    Location:886
    PseudoU_synth_RluCD_like; Pseudouridine synthase, RsuA/RluD family
  8. NM_001369658.1NP_001356587.1  RNA pseudouridylate synthase domain-containing protein 1 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AL031033
    Conserved Domains (1) summary
    cd02869
    Location:18199
    PseudoU_synth_RluCD_like; Pseudouridine synthase, RsuA/RluD family
  9. NM_001369659.1NP_001356588.1  RNA pseudouridylate synthase domain-containing protein 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL031033
    Conserved Domains (1) summary
    cd02869
    Location:989
    PseudoU_synth_RluCD_like; Pseudouridine synthase, RsuA/RluD family
  10. NM_001369660.1NP_001356589.1  RNA pseudouridylate synthase domain-containing protein 1 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AL031033
    Conserved Domains (1) summary
    cd02869
    Location:886
    PseudoU_synth_RluCD_like; Pseudouridine synthase, RsuA/RluD family
  11. NM_058192.3NP_478072.1  RNA pseudouridylate synthase domain-containing protein 1 isoform 1

    See identical proteins and their annotated locations for NP_478072.1

    Status: VALIDATED

    Source sequence(s)
    BC011783, BG686882, BM763460, CB529100
    Consensus CDS
    CCDS10426.1
    UniProtKB/Swiss-Prot
    Q9UJJ7
    Related
    ENSP00000007264.2, ENST00000007264.7
    Conserved Domains (2) summary
    cd02869
    Location:18215
    PseudoU_synth_RluCD_like; Pseudouridine synthase, RsuA/RluD family
    COG0564
    Location:9230
    RluA; Pseudouridylate synthase, 23S rRNA- or tRNA-specific [Translation, ribosomal structure and biogenesis]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    784974..788381 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024450144.1XP_024305912.1  RNA pseudouridylate synthase domain-containing protein 1 isoform X1

    Conserved Domains (1) summary
    cd02869
    Location:18103
    PseudoU_synth_RluCD_like; Pseudouridine synthase, RsuA/RluD family
Support Center