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GLB1L3 galactosidase beta 1 like 3 [ Homo sapiens (human) ]

Gene ID: 112937, updated on 12-Oct-2019

Summary

Official Symbol
GLB1L3provided by HGNC
Official Full Name
galactosidase beta 1 like 3provided by HGNC
Primary source
HGNC:HGNC:25147
See related
Ensembl:ENSG00000166105
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in prostate (RPKM 3.4), testis (RPKM 1.2) and 7 other tissues See more
Orthologs

Genomic context

See GLB1L3 in Genome Data Viewer
Location:
11q25
Exon count:
26
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (134272716..134325307)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (134145293..134189458)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene thymocyte nuclear protein 1 Neighboring gene acyl-CoA dehydrogenase family member 8 Neighboring gene ATPase H+/K+ transporting subunit beta pseudogene Neighboring gene galactosidase beta 1 like 2 Neighboring gene beta-1,3-glucuronyltransferase 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

NHGRI GWAS Catalog

Description
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ90231

Gene Ontology Provided by GOA

Function Evidence Code Pubs
beta-galactosidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
vacuole IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
beta-galactosidase-1-like protein 3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080407.3NP_001073876.2  beta-galactosidase-1-like protein 3

    See identical proteins and their annotated locations for NP_001073876.2

    Status: VALIDATED

    Source sequence(s)
    AK074712, AP000859, BC011001, BC040605, CX760372
    Consensus CDS
    CCDS44780.1
    UniProtKB/Swiss-Prot
    Q8NCI6
    Related
    ENSP00000396615.2, ENST00000431683.7
    Conserved Domains (2) summary
    pfam01301
    Location:80388
    Glyco_hydro_35; Glycosyl hydrolases family 35
    pfam13364
    Location:559631
    BetaGal_dom4_5; Beta-galactosidase jelly roll domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    134272716..134325307
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017017156.2XP_016872645.1  beta-galactosidase-1-like protein 3 isoform X8

  2. XM_017017155.2XP_016872644.1  beta-galactosidase-1-like protein 3 isoform X4

  3. XM_011542567.2XP_011540869.1  beta-galactosidase-1-like protein 3 isoform X2

    Conserved Domains (2) summary
    pfam01301
    Location:127435
    Glyco_hydro_35; Glycosyl hydrolases family 35
    pfam13364
    Location:606678
    BetaGal_dom4_5; Beta-galactosidase jelly roll domain
  4. XM_011542566.2XP_011540868.1  beta-galactosidase-1-like protein 3 isoform X1

    Conserved Domains (2) summary
    pfam01301
    Location:127435
    Glyco_hydro_35; Glycosyl hydrolases family 35
    pfam13364
    Location:606678
    BetaGal_dom4_5; Beta-galactosidase jelly roll domain
  5. XM_011542569.2XP_011540871.1  beta-galactosidase-1-like protein 3 isoform X5

    Conserved Domains (2) summary
    pfam13364
    Location:469541
    BetaGal_dom4_5; Beta-galactosidase jelly roll domain
    cl07893
    Location:127353
    AmyAc_family; Alpha amylase catalytic domain family
  6. XM_011542568.2XP_011540870.1  beta-galactosidase-1-like protein 3 isoform X3

    Conserved Domains (2) summary
    pfam01301
    Location:127423
    Glyco_hydro_35; Glycosyl hydrolases family 35
    pfam13364
    Location:594666
    BetaGal_dom4_5; Beta-galactosidase jelly roll domain
  7. XM_011542570.2XP_011540872.1  beta-galactosidase-1-like protein 3 isoform X6

    Conserved Domains (2) summary
    pfam13364
    Location:457529
    BetaGal_dom4_5; Beta-galactosidase jelly roll domain
    cl07893
    Location:127341
    AmyAc_family; Alpha amylase catalytic domain family
  8. XM_011542571.2XP_011540873.1  beta-galactosidase-1-like protein 3 isoform X7

    Conserved Domains (1) summary
    pfam01301
    Location:127435
    Glyco_hydro_35; Glycosyl hydrolases family 35
  9. XM_024448338.1XP_024304106.1  beta-galactosidase-1-like protein 3 isoform X11

    Conserved Domains (2) summary
    cl07893
    Location:36139
    AmyAc_family; Alpha amylase catalytic domain family
    cl26201
    Location:47388
    GanA; Beta-galactosidase GanA [Carbohydrate transport and metabolism]
  10. XM_011542572.1XP_011540874.1  beta-galactosidase-1-like protein 3 isoform X9

    Conserved Domains (2) summary
    pfam13364
    Location:322394
    BetaGal_dom4_5; Beta-galactosidase jelly roll domain
    cl07893
    Location:1151
    AmyAc_family; Alpha amylase catalytic domain family
  11. XM_011542574.2XP_011540876.1  beta-galactosidase-1-like protein 3 isoform X12

    Conserved Domains (2) summary
    pfam13364
    Location:289361
    BetaGal_dom4_5; Beta-galactosidase jelly roll domain
    cl07893
    Location:15118
    AmyAc_family; Alpha amylase catalytic domain family
  12. XM_011542573.1XP_011540875.1  beta-galactosidase-1-like protein 3 isoform X10

    Conserved Domains (2) summary
    pfam13364
    Location:320392
    BetaGal_dom4_5; Beta-galactosidase jelly roll domain
    cl07893
    Location:46149
    AmyAc_family; Alpha amylase catalytic domain family

RNA

  1. XR_002957120.1 RNA Sequence

  2. XR_947791.2 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_138416.1: Suppressed sequence

    Description
    NM_138416.1: This RefSeq was permanently suppressed because its last exon is unsupported and it appears to be a partial representation of this gene.
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