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LOC112935931 Sharpr-MPRA regulatory region 4455 [ Homo sapiens (human) ]

Gene ID: 112935931, updated on 21-Dec-2019

Summary

Gene symbol
LOC112935931
Gene description
Sharpr-MPRA regulatory region 4455
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence was predicted to be a transcriptional regulatory region based on chromatin state analysis from the ENCODE (ENCyclopedia Of DNA Elements) project. It was validated as a functional enhancer by the Sharpr-MPRA technique (Systematic high-resolution activation and repression profiling with reporter tiling using massively parallel reporter assays) in both HepG2 liver carcinoma cells (group: HepG2 Activating non-DNase unmatched - State 23:Low, low signal proximal to active elements) and K562 erythroleukemia cells (group: K562 Activating DNase matched - State 5:Enh, candidate strong enhancer, open chromatin). [provided by RefSeq, Aug 2018]

Genomic context

See LOC112935931 in Genome Data Viewer
Location:
3p
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (4340585..4340879)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene sulfatase modifying factor 1 Neighboring gene uncharacterized LOC107986008 Neighboring gene SET domain and mariner transposase fusion gene Neighboring gene mitochondrial ribosomal protein S10 pseudogene 2 Neighboring gene ITPR1 divergent transcript

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_061447.1 

    Range
    101..395
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    4340585..4340879
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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