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BRCA1 BRCA1 DNA repair associated [ Vulpes vulpes (red fox) ]

Gene ID: 112910801, updated on 15-Mar-2024

Summary

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Gene symbol
BRCA1
Gene description
BRCA1 DNA repair associated
See related
Ensembl:ENSVVUG00000023972
Gene type
protein coding
RefSeq status
MODEL
Organism
Vulpes vulpes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
100 current VulVul2.2 (GCF_003160815.1) Unplaced Scaffold NW_020356676.1 (1538827..1604537, complement)

NW_020356676.1Genomic Context describing neighboring genes Neighboring gene vesicle amine transport 1 Neighboring gene Rho family GTPase 2 Neighboring gene NBR1 autophagy cargo receptor Neighboring gene transmembrane protein 106A

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020356676 Unplaced Scaffold Reference VulVul2.2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chordate embryonic development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in dosage compensation by inactivation of X chromosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of BRCA1-A complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of BRCA1-BARD1 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
breast cancer type 1 susceptibility protein
Names
breast and ovarian cancer susceptibility protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Vulpes vulpes Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VulVul2.2 Primary Assembly

Genomic

  1. NW_020356676.1 Reference VulVul2.2 Primary Assembly

    Range
    1538827..1604537 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025987104.1 → XP_025842889.1  breast cancer type 1 susceptibility protein

    UniProtKB/TrEMBL
    A0A3Q7RA52
    Related
    ENSVVUP00000033149.1, ENSVVUT00000043777.1
    Conserved Domains (5) summary
    smart00292
    Location:1766 → 1850
    BRCT; breast cancer carboxy-terminal domain
    pfam00533
    Location:1668 → 1726
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam12820
    Location:344 → 506
    BRCT_assoc; Serine-rich domain associated with BRCT
    cd16498
    Location:18 → 65
    RING-HC_BRCA1; RING finger, HC subclass, found in breast cancer type 1 susceptibility protein (BRCA1) and similar proteins
    cl28410
    Location:15 → 121
    RAD18; RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]
Nucleotide Protein Strain
Heading Accession and Version

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