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PRAF2 PRA1 domain family member 2 [ Homo sapiens (human) ]

Gene ID: 11230, updated on 17-Jun-2019

Summary

Official Symbol
PRAF2provided by HGNC
Official Full Name
PRA1 domain family member 2provided by HGNC
Primary source
HGNC:HGNC:28911
See related
Ensembl:ENSG00000243279 MIM:300840
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
JM4; Yip6a
Expression
Ubiquitous expression in brain (RPKM 27.2), testis (RPKM 14.5) and 24 other tissues See more
Orthologs

Genomic context

See PRAF2 in Genome Data Viewer
Location:
Xp11.23
Exon count:
3
Annotation release Status Assembly Chr Location
109.20190607 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (49071161..49074002, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (48928818..48931662, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene transcription factor binding to IGHM enhancer 3 Neighboring gene Sharpr-MPRA regulatory region 2669 Neighboring gene coiled-coil domain containing 120 Neighboring gene WD repeat domain 45 Neighboring gene RNA, U4 small nuclear 52, pseudogene Neighboring gene G-patch domain and KOW motifs

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Envelope surface glycoprotein gp160, precursor env HIV-1 gp160 interacts with PRAF2; predicted interaction to be within the endoplasmic reticulum to Golgi transport PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: WDR45

Homology

Clone Names

  • FLJ57916

Gene Ontology Provided by GOA

Process Evidence Code Pubs
L-glutamate transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
 
protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
endosome membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
PRA1 family protein 2
Names
Jena-Muenchen 4

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007213.3NP_009144.1  PRA1 family protein 2

    See identical proteins and their annotated locations for NP_009144.1

    Status: VALIDATED

    Source sequence(s)
    AC231657, AJ005896
    Consensus CDS
    CCDS14317.1
    UniProtKB/Swiss-Prot
    O60831
    UniProtKB/TrEMBL
    A0A024QZ22
    Related
    ENSP00000451962.2, ENST00000553851.3
    Conserved Domains (1) summary
    pfam03208
    Location:4149
    PRA1; PRA1 family protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    49071161..49074002 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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