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ANXA10 annexin A10 [ Homo sapiens (human) ]

Gene ID: 11199, updated on 17-Sep-2024

Summary

Official Symbol
ANXA10provided by HGNC
Official Full Name
annexin A10provided by HGNC
Primary source
HGNC:HGNC:534
See related
Ensembl:ENSG00000109511 MIM:608008; AllianceGenome:HGNC:534
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ANX14
Summary
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The function of this gene has not yet been determined. [provided by RefSeq, Jul 2008]
Expression
Biased expression in stomach (RPKM 190.8), urinary bladder (RPKM 26.5) and 1 other tissue See more
Orthologs
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Genomic context

See ANXA10 in Genome Data Viewer
Location:
4q32.3
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (168092537..168187736)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (171451471..171546783)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (169013688..169108887)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene RN7SK pseudogene 188 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:168778932-168779432 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:168797178-168797908 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr4:168817975-168819174 Neighboring gene uncharacterized LOC105377523 Neighboring gene uncharacterized LOC124900170 Neighboring gene uncharacterized LOC105377524 Neighboring gene DExD/H-box helicase 60 Neighboring gene small nucleolar RNA U13 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22124 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_76106 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_76110 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_76113 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_76114 Neighboring gene DExD/H-box 60 like Neighboring gene small nucleolar RNA SNORA51

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
enables calcium-dependent phospholipid binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables phosphatidylserine binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in vesicle membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
annexin A10
Names
annexin 14
annexin-10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007193.5NP_009124.2  annexin A10

    See identical proteins and their annotated locations for NP_009124.2

    Status: REVIEWED

    Source sequence(s)
    AC068989, BC007320, BM768053
    Consensus CDS
    CCDS34096.1
    UniProtKB/Swiss-Prot
    Q96IQ5, Q9UJ72, Q9UJV4
    Related
    ENSP00000352248.3, ENST00000359299.8
    Conserved Domains (1) summary
    pfam00191
    Location:93158
    Annexin; Annexin

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    168092537..168187736
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011531571.3XP_011529873.1  annexin A10 isoform X1

    Conserved Domains (1) summary
    pfam00191
    Location:113178
    Annexin; Annexin

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    171451471..171546783
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054348837.1XP_054204812.1  annexin A10 isoform X1