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LOC111591507 GATA motif-containing MPRA enhancer 295 [ Homo sapiens (human) ]

Gene ID: 111591507, updated on 17-Jun-2019

Summary

Gene symbol
LOC111591507
Gene description
GATA motif-containing MPRA enhancer 295
Gene type
biological region
Feature type(s)
regulatory: enhancer, transcriptional_cis_regulatory_region
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was predicted to be a cell type-specific enhancer based on chromatin state analysis from the ENCODE (ENCyclopedia Of DNA Elements) project. It was validated as a functional enhancer by high-throughput massively parallel reporter assays (MPRAs) in K562 erythroleukemia cells. This enhancer contains a motif for a GATA activator. Mutation of this motif results in reduced enhancer activity. [provided by RefSeq, Dec 2017]

Genomic context

See LOC111591507 in Genome Data Viewer
Location:
3p
Annotation release Status Assembly Chr Location
109.20190607 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (49349802..49349946)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene chromosome 3 open reading frame 62 Neighboring gene microRNA 4271 Neighboring gene ubiquitin specific peptidase 4 Neighboring gene Sjoegren syndrome nuclear autoantigen 1 homolog Neighboring gene glutathione peroxidase 1 Neighboring gene ras homolog family member A

Genomic regions, transcripts, and products

General gene information

Other Names

  • GATA activator MPRA enhancer 295
  • massively parallel reporter assay enhancer 295

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_056098.1 

    Range
    101..245
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    49349802..49349946
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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