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LYNX1-SLURP2 LYNX1-SLURP2 readthrough [ Homo sapiens (human) ]

Gene ID: 111188157, updated on 15-Mar-2024

Summary

Official Symbol
LYNX1-SLURP2provided by HGNC
Official Full Name
LYNX1-SLURP2 readthroughprovided by HGNC
Primary source
HGNC:HGNC:52291
See related
Ensembl:ENSG00000284505 AllianceGenome:HGNC:52291
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This locus represents naturally occurring read-through transcription between the neighboring LYNX1 and SLURP2 genes. The readthrough transcript encodes a fusion protein comprised of sequence sharing identity with each individual gene product. The significance of this read-through transcription and the function of the resulting protein product have not yet been determined. [provided by RefSeq, Sep 2017]
Orthologs
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Genomic context

See LYNX1-SLURP2 in Genome Data Viewer
Location:
8q24.3
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (142764338..142777872, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (143907780..143921325, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (143845756..143859288, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene secreted LY6/PLAUR domain containing 1 Neighboring gene LY6/PLAUR domain containing 2 Neighboring gene uncharacterized LOC124902033 Neighboring gene secreted LY6/PLAUR domain containing 2 Neighboring gene Ly6/neurotoxin 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19608 Neighboring gene lymphocyte antigen 6 family member D Neighboring gene MED14-independent group 3 enhancer GRCh37_chr8:143896321-143897520 Neighboring gene glycosylphosphatidylinositol anchored molecule like

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023946.5NP_076435.1  LYNX1-SLURP2 protein precursor

    See identical proteins and their annotated locations for NP_076435.1

    Status: REVIEWED

    Source sequence(s)
    AC083841, BC032306
    UniProtKB/Swiss-Prot
    P0DP58
    Related
    ENSP00000479586.1, ENST00000615007.4
    Conserved Domains (1) summary
    cd00117
    Location:58131
    LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    142764338..142777872 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    143907780..143921325 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)