Iglc2 immunoglobulin lambda constant 2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Iglc2provided by MGI
Official Full Name: immunoglobulin lambda constant 2provided by MGI
Primary source: MGI:MGI:99547
See related: Ensembl:ENSMUSG00000076937 IMGT/GENE-DB:IGLC2; AllianceGenome:MGI:99547
Gene type: other
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Igl-C2
Summary: Predicted to enable antigen binding activity. Predicted to be involved in immunoglobulin mediated immune response. Predicted to be located in extracellular region and plasma membrane. Predicted to be part of IgG immunoglobulin complex. Orthologous to human IGLC2 (immunoglobulin lambda constant 2); IGLC3 (immunoglobulin lambda constant 3 (Kern-Oz+ marker)); and IGLC6 (immunoglobulin lambda constant 6). [provided by Alliance of Genome Resources, Mar 2025]
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Genomic context

Location:: 16 A3; 16 11.89 cM

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	16	NC_000082.7 (19017286..19017602, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	16	NC_000082.6 (19198536..19198852, complement)

Chromosome 16 - NC_000082.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Other Names

immunoglobulin lambda chain, constant region 2
immunoglobulin lambda-chain

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables antigen binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in immunoglobulin mediated immune response	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of IgG immunoglobulin complex	IBA Inferred from Biological aspect of Ancestor more info
part_of IgG immunoglobulin complex	ISO Inferred from Sequence Orthology more info
located_in extracellular region	TAS Traceable Author Statement more info
located_in plasma membrane	TAS Traceable Author Statement more info

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.