Iglc1 immunoglobulin lambda constant 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Iglc1provided by MGI
Official Full Name: immunoglobulin lambda constant 1provided by MGI
Primary source: MGI:MGI:99546
See related: Ensembl:ENSMUSG00000105906 IMGT/GENE-DB:IGLC1; AllianceGenome:MGI:99546
Gene type: other
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Igl-C1; Clambda1
Summary: Predicted to enable antigen binding activity. Predicted to be involved in immunoglobulin mediated immune response. Located in external side of plasma membrane. Part of B cell receptor complex. Orthologous to several human genes including IGLC6 (immunoglobulin lambda constant 6). [provided by Alliance of Genome Resources, Mar 2025]
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Genomic context

Location:: 16 A3; 16 11.8 cM

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	16	NC_000082.7 (18880502..18880821, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	16	NC_000082.6 (19061752..19062071, complement)

Chromosome 16 - NC_000082.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (3) 1 citation

General gene information

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Markers

AI528645 (e-PCR)
- UniSTS:209178

M94351 (e-PCR)
- UniSTS:125002

AW494620 (e-PCR)
- UniSTS:180875

Other Names

immunoglobulin lambda chain, constant region 1

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables antigen binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in immunoglobulin mediated immune response	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of B cell receptor complex	IDA Inferred from Direct Assay more info	PubMed
part_of IgG immunoglobulin complex	IBA Inferred from Biological aspect of Ancestor more info
part_of IgG immunoglobulin complex	ISO Inferred from Sequence Orthology more info
located_in external side of plasma membrane	IDA Inferred from Direct Assay more info	PubMed

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.