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Hivep1 human immunodeficiency virus type I enhancer binding protein 1 [ Mus musculus (house mouse) ]

Gene ID: 110521, updated on 8-Dec-2022

Summary

Official Symbol
Hivep1provided by MGI
Official Full Name
human immunodeficiency virus type I enhancer binding protein 1provided by MGI
Primary source
MGI:MGI:96100
See related
Ensembl:ENSMUSG00000021366 AllianceGenome:MGI:96100
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Cryabp1
Summary
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; HMG box domain binding activity; and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; hemolymphoid system gland; and musculoskeletal system. Orthologous to human HIVEP1 (HIVEP zinc finger 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in lung adult (RPKM 7.2), colon adult (RPKM 7.1) and 28 other tissues See more
Orthologs
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Genomic context

See Hivep1 in Genome Data Viewer
Location:
13 A4; 13 20.72 cM
Exon count:
13
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (42205304..42338504)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (42051899..42185030)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32555 Neighboring gene predicted gene 28707 Neighboring gene predicted gene, 32778 Neighboring gene VISTA enhancer mm235

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3) 
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
zinc finger protein 40
Names
HIV type I enhancer binding protein 1
alpha A-CRYBP1
alpha A-crystallin-binding protein 1
alpha A-crystallin-binding protein I
alphaA-CRYBP1
crystallin, alpha binding protein 1
transcription factor alphaA-CRYBP1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007772.2NP_031798.2  zinc finger protein 40

    See identical proteins and their annotated locations for NP_031798.2

    Status: VALIDATED

    Source sequence(s)
    AC159258
    Consensus CDS
    CCDS36643.1
    UniProtKB/TrEMBL
    F8VPM9
    Related
    ENSMUSP00000056147.6, ENSMUST00000060148.6
    Conserved Domains (5) summary
    sd00017
    Location:409429
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:20762096
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:20742096
    zf-C2H2; Zinc finger, C2H2 type
    pfam12756
    Location:21022167
    zf-C2H2_2; C2H2 type zinc-finger (2 copies)
    pfam13465
    Location:422446
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    42205304..42338504
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006516839.5XP_006516902.1  zinc finger protein 40 isoform X1

    See identical proteins and their annotated locations for XP_006516902.1

    Conserved Domains (6) summary
    smart00451
    Location:20992130
    ZnF_U1; U1-like zinc finger
    PHA03247
    Location:22982691
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:409429
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:20762096
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:20742096
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:422446
    zf-H2C2_2; Zinc-finger double domain
  2. XM_006516840.5XP_006516903.1  zinc finger protein 40 isoform X1

    See identical proteins and their annotated locations for XP_006516903.1

    Conserved Domains (6) summary
    smart00451
    Location:20992130
    ZnF_U1; U1-like zinc finger
    PHA03247
    Location:22982691
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:409429
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:20762096
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:20742096
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:422446
    zf-H2C2_2; Zinc-finger double domain
  3. XM_017315358.3XP_017170847.1  zinc finger protein 40 isoform X1

    Conserved Domains (6) summary
    smart00451
    Location:20992130
    ZnF_U1; U1-like zinc finger
    PHA03247
    Location:22982691
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:409429
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:20762096
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:20742096
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:422446
    zf-H2C2_2; Zinc-finger double domain
  4. XM_030247127.2XP_030102987.1  zinc finger protein 40 isoform X2

    Conserved Domains (6) summary
    smart00451
    Location:19822013
    ZnF_U1; U1-like zinc finger
    PHA03247
    Location:21812574
    PHA03247; large tegument protein UL36; Provisional
    sd00017
    Location:292312
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:19591979
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:19571979
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:305329
    zf-H2C2_2; Zinc-finger double domain