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Krt5 keratin 5 [ Mus musculus (house mouse) ]

Gene ID: 110308, updated on 4-Sep-2018

Summary

Official Symbol
Krt5provided by MGI
Official Full Name
keratin 5provided by MGI
Primary source
MGI:MGI:96702
See related
Ensembl:ENSMUSG00000061527 Vega:OTTMUSG00000028033
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
K5; CK5; Tfip8; Krt2-5; AW146334; 3300001P10Rik
Expression
Biased expression in bladder adult (RPKM 193.4), limb E14.5 (RPKM 123.9) and 6 other tissues See more
Orthologs

Genomic context

See Krt5 in Genome Data Viewer
Location:
15 F2; 15 56.98 cM
Exon count:
9
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 15 NC_000081.6 (101707070..101712891, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (101537501..101543322, complement)

Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene keratin 6B Neighboring gene keratin 6A Neighboring gene keratin 71 Neighboring gene keratin 74

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (4)  1 citation
  • Endonuclease-mediated (1) 

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
scaffold protein binding ISO
Inferred from Sequence Orthology
more info
 
structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
intermediate filament ISO
Inferred from Sequence Orthology
more info
 
keratin filament IDA
Inferred from Direct Assay
more info
PubMed 
keratin filament ISO
Inferred from Sequence Orthology
more info
PubMed 
mitochondrion HDA PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
keratin, type II cytoskeletal 5
Names
58 kDa cytokeratin
cytokeratin 5
keratin complex 2, basic, gene 5
tuftelin interacting protein 8
type-II keratin Kb5

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027011.3NP_081287.1  keratin, type II cytoskeletal 5

    See identical proteins and their annotated locations for NP_081287.1

    Status: VALIDATED

    Source sequence(s)
    AC104862, AC120787
    Consensus CDS
    CCDS27861.1
    UniProtKB/Swiss-Prot
    Q922U2
    UniProtKB/TrEMBL
    Q32P04
    Related
    ENSMUSP00000023709.5, OTTMUSP00000035258, ENSMUST00000023709.6
    Conserved Domains (3) summary
    pfam00038
    Location:161474
    Filament; Intermediate filament protein
    pfam16208
    Location:16158
    Keratin_2_head; Keratin type II head
    cl01888
    Location:387447
    DUF883; Bacterial protein of unknown function (DUF883)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000081.6 Reference GRCm38.p4 C57BL/6J

    Range
    101707070..101712891 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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