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SCO5892 polyketide synthase [ Streptomyces coelicolor A3(2) ]

Gene ID: 1101334, discontinued on 9-Sep-2022
  • This record was discontinued.

Summary

Gene symbol
SCO5892
Gene description
polyketide synthase
Locus tag
SCO5892
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Streptomyces coelicolor A3(2) (serovar: A3(2))
Lineage
Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group
Also known as
redL; SC3F7.12
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General gene information

Miscellaneous features

  • Loc: 6449729-6451084 Pfam match to entry AMP-binding PF00501, AMP-binding enzymes, from 1 to 415, score 166.66
  • Loc: 6451946-6453175 Pfam match to entry ketoacyl-synt PF00109, Beta-ketoacyl synthases, from 1 to 442, score 585.24
  • Loc: 6452384-6452434 PS00606 Beta-ketoacyl synthases active site
  • Loc: 6455525-6456379 Pfam match to entry aminotran_2 PF00222, Aminotransferases class-II, from 1 to 292, score 276.93
  • Loc: 6455996-6456025 PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site

General protein information

Names
polyketide synthase
NP_630013.1
  • SC3F7.12, redL, probable polyketide synthase, len: 2297 aa; contains 3 modules: N-terminus (start to approx. aa 700) similar to eg. N-terminus of TR:Q50857 (EMBL:U24657) saframycin mx1 synthetase B from Myxococcus xanthus (1770 aa) (fasta scores; E(): 0, 45.0% identity in 691 aa overlap), contains Pfam match to AMP-binding PF00501, AMP-binding enzymes, score 166.66; central module (approx aa 795 to 1800) similar to eg. TR:G2317861 (EMBL:U78289) Streptomyces fradiae tylactone synthase module 3 (1864 aa) (E(): 0, 39.9% identity in 1125 aa overlap), contains PS00606 Beta-ketoacyl synthases active site and Pfam match to ketoacyl-synt PF00109, Beta-ketoacyl synthases, score 585.24; and C-terminus (approx aa 1800 to end), similar to eg. TR:Q52936 (EMBL:X64131 acyl-transferase rkpG from Rhizobium meliloti (446 aa) (E(): 0. 44.9% identity in 394 aa overlap), contains PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site and Pfam match to aminotran_2 PF00222, Aminotransferases class-II, score 276.93

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003888.3 Reference assembly

    Range
    6449549..6456442
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_630013.1 polyketide synthase [Streptomyces coelicolor A3(2)]

    Status: REVIEWED