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CFAP298-TCP10L CFAP298-TCP10L readthrough [ Homo sapiens (human) ]

Gene ID: 110091775, updated on 21-Mar-2023

Summary

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Official Symbol
CFAP298-TCP10Lprovided by HGNC
Official Full Name
CFAP298-TCP10L readthroughprovided by HGNC
Primary source
HGNC:HGNC:54636
See related
Ensembl:ENSG00000265590 AllianceGenome:HGNC:54636
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C21orf77; LINC00846; C21orf59-TCP10L
Summary
This locus represents naturally occurring readthrough transcription between the neighboring chromosome 21 open reading frame 59 (C21orf59) and TCP10L (t-complex 10 like) genes on chromosome 21. Readthrough transcripts may encode a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Apr 2017]
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Genomic context

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See CFAP298-TCP10L in Genome Data Viewer
Location:
21q22.11
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_03 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (32563492..32612377, complement)
RS_2023_03 current T2T-CHM13v2.0 (GCF_009914755.1) 21 NC_060945.1 (30923998..30978378, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (33935802..33984687, complement)

Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene eva-1 homolog C Neighboring gene exosome component 3 pseudogene 1 Neighboring gene RNA, 5S ribosomal pseudogene 490 Neighboring gene t-complex 10 like Neighboring gene cilia and flagella associated protein 298 Neighboring gene olfactory receptor family 7 subfamily E member 23 pseudogene Neighboring gene synaptojanin 1 Neighboring gene uncharacterized LOC124905011

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions. Denoeud F, et al. Genome Res, 2007 Jun. PMID 17567994, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

Genotypes

General gene information

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Homology

General protein information

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Preferred Names
uncharacterized protein LOC110091775
Names
C21orf59-TCP10L readthrough
long intergenic non-protein coding RNA 846

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001350338.2 → NP_001337267.1  uncharacterized protein LOC110091775

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes a protein with similarity to the proteins encoded by C21orf59 and TCP10L.
    Source sequence(s)
    AP000274, AP000275
    UniProtKB/TrEMBL
    A0A669KAY3
    Related
    ENSP00000501088.1, ENST00000673807.1
    Conserved Domains (1) summary
    pfam11069
    Location:189 → 219
    DUF2870; Protein of unknown function (DUF2870)

RNA

  1. NR_146638.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP000274, AP000275

  2. NR_146639.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP000274, AP000275

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_03

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

    Range
    32563492..32612377 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060945.1 Alternate T2T-CHM13v2.0

    Range
    30923998..30978378 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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