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SCO5086 ketoacyl reductase [ Streptomyces coelicolor A3(2) ]

Gene ID: 1100527, discontinued on 9-Sep-2022
  • This record was discontinued.
Gene symbol
SCO5086
Gene description
ketoacyl reductase
Locus tag
SCO5086
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Streptomyces coelicolor A3(2) (serovar: A3(2))
Lineage
Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group
Also known as
actIII; SCBAC28G1.12c
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Genomic Sequence:
NC_003888.3

Go to nucleotide: Graphics FASTA GenBank

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ActIII is a cytosolic protein, with limited association with the membrane or cell wall.
    Title: Green fluorescent protein as a reporter for the spatial and temporal expression of actIII in Streptomyces coelicolor.
  2. Crystall structure of polyketide ketoreductase (actIII) with its bound cofactor, NADP+, was determined.
    Title: The crystal structure of the actIII actinorhodin polyketide reductase: proposed mechanism for ACP and polyketide binding.
  3. support the cell-wall location of ketoreductase
    Title: Localization of the ActIII actinorhodin polyketide ketoreductase to the cell wall.
  4. cloning and x-ray diffraction analysis of Streptomyces coelicolor actIII
    Title: Expression, purification and preliminary X-ray diffraction analysis of a ketoreductase from a type II polyketide synthase.
Submit: New GeneRIF Correction

Miscellaneous features

  • Loc: c5529051-5528959 Pfam match to entry PF00678 adh_short_C2, Short chain dehydrogenase/reductase C-terminus, score 25.80, E-value 1.4e-05
  • Loc: c5529291-5529205 PS00061 Short-chain dehydrogenases/reductases family signature
  • Loc: c5529702-5529142 Pfam match to entry PF00106 adh_short, short chain dehydrogenase, score 302.10, E-value 6.8e-87
Names
ketoacyl reductase
NP_629236.1
  • SCBAC28G1.12c, actIII, ketoacyl reductase, len: 261 aa; identical to previously sequenced SW:ACT3_STRCO (EMBL:M19536) Streptomyces coelicolor ketoacyl reductase ActIII, 261 aa. Contains Pfam matches to entries PF00106 adh_short, short chain dehydrogenase and PF00678 adh_short_C2, Short chain dehydrogenase/reductase C-terminus and match to Prosite entry PS00061 Short-chain dehydrogenases/reductases family signature

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003888.3 Reference assembly

    Range
    5528935..5529720 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_629236.1 ketoacyl reductase [Streptomyces coelicolor A3(2)]

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P16544.1

Gene LinkOut

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