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SCO4426 regulatory protein [ Streptomyces coelicolor A3(2) ]

Gene ID: 1099866, discontinued on 9-Sep-2022
  • This record was discontinued.
Gene symbol
SCO4426
Gene description
regulatory protein
Locus tag
SCO4426
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Streptomyces coelicolor A3(2) (serovar: A3(2))
Lineage
Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group
Also known as
afsR; SCD6.04c
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Genomic Sequence:
NC_003888.3

Go to nucleotide: Graphics FASTA GenBank

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Both PhoP and AfsR proteins are able to bind to overlapping regions within the glnR promoter producing different effects.
    Title: Overlapping binding of PhoP and AfsR to the promoter region of glnR in Streptomyces coelicolor.
  2. PhoP and AfsR compete for overlapping sequences in the afsS promoter. AfsR also regulates regulate the PhoR-PhoP system and represses the pstS gene.
    Title: Cross-talk between two global regulators in Streptomyces: PhoP and AfsR interact in the control of afsS, pstS and phoRP transcription.
  3. findings show that two AfsR monomers bind to the direct repeats on the afsS promoter, recruit RNAP to the promoter, and subsequently form a DNA-(AfsR)2-RNAP complex
    Title: AfsR recruits RNA polymerase to the afsS promoter: a model for transcriptional activation by SARPs.
Submit: New GeneRIF Correction

Miscellaneous features

  • Loc: c4844781-4844758 PS00017 ATP/GTP-binding site motif A (P-loop)
Names
regulatory protein
NP_628593.1
  • SCD6.04c, afsR, regulatory protein, len: 993 aa; identical to previously sequenced SW:AFSR_STRCO (EMBL:D90155) Streptomyces coelicolor regulatory protein AfsR, 993 aa. Contains match to Prosite entry PS00017 ATP/GTP-binding site motif A (P-loop)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003888.3 Reference assembly

    Range
    4842787..4845768 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_628593.1 regulatory protein [Streptomyces coelicolor A3(2)]

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P25941.2

Gene LinkOut

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