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bldA tRNA-Leu [ Streptomyces coelicolor A3(2) ]

Gene ID: 1098521, discontinued on 9-Sep-2022
  • This record was discontinued.
Gene symbol
bldA
Gene description
tRNA-Leu
Locus tag
SCOt24
Gene type
tRNA
Organism
Streptomyces coelicolor A3(2) (serovar: A3(2))
Lineage
Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group
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Genomic Sequence:
NC_003888.3

Go to nucleotide: Graphics FASTA GenBank

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. BldA tRNA scaffold is not critical for function as a regulator of S. coelicolor cell differentiation.
    Title: tRNA accumulation and suppression of the bldA phenotype during development in Streptomyces coelicolor.
  2. In Streptomyces coelicolor, bldA encodes the only tRNA for a rare leucine codon, UUA and this tRNA is unnecessary for growth, but is required for secondary metabolism and morphological development.
    Title: The use of the rare UUA codon to define "expression space" for genes involved in secondary metabolism, development and environmental adaptation in streptomyces.
  3. Mutation in bldA induced changes in the extracellular proteome, revealing even greater pleiotropy in the bldA phenotype than previously known.
    Title: Changes in the extracellular proteome caused by the absence of the bldA gene product, a developmentally significant tRNA, reveal a new target for the pleiotropic regulator AdpA in Streptomyces coelicolor.
Submit: New GeneRIF Correction
  • tRNA Leu anticodon TAA (bldA), Cove score 58.78