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Pgc progastricsin (pepsinogen C) [ Mus musculus (house mouse) ]

Gene ID: 109820, updated on 23-May-2018
Official Symbol
Pgcprovided by MGI
Official Full Name
progastricsin (pepsinogen C)provided by MGI
Primary source
MGI:MGI:98909
See related
Ensembl:ENSMUSG00000023987 Vega:OTTMUSG00000018356
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Upg1; Upg-1; 2210410L06Rik
Expression
Restricted expression toward duodenum adult (RPKM 123.5) See more
Orthologs
See Pgc in Genome Data Viewer
Location:
17 C; 17 23.98 cM
Exon count:
9
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (47726842..47734478)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (47863791..47871427)

Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene fibroblast growth factor receptor substrate 3 Neighboring gene fibroblast growth factor receptor substrate 3, opposite strand Neighboring gene predicted gene, 46579 Neighboring gene transcription factor EB Neighboring gene MyoD family inhibitor

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 

Markers

Homology

Clone Names

  • MGC117575

Gene Ontology Provided by MGI

Function Evidence Code Pubs
aspartic-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
aspartic-type endopeptidase activity ISO
Inferred from Sequence Orthology
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
peptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
digestion IEA
Inferred from Electronic Annotation
more info
 
positive regulation of antibacterial peptide production ISO
Inferred from Sequence Orthology
more info
 
proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
gastricsin
Names
pepsinogen C
urinary pepsinogen 1
NP_080249.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025973.3NP_080249.2  gastricsin precursor

    See identical proteins and their annotated locations for NP_080249.2

    Status: PROVISIONAL

    Source sequence(s)
    AK008959
    Consensus CDS
    CCDS28855.1
    UniProtKB/Swiss-Prot
    Q9D7R7
    Related
    ENSMUSP00000024782.5, OTTMUSP00000019927, ENSMUST00000024782.11, OTTMUST00000044343
    Conserved Domains (3) summary
    pfam00026
    Location:75390
    Asp; Eukaryotic aspartyl protease
    pfam07966
    Location:1846
    A1_Propeptide; A1 Propeptide
    cl11403
    Location:73391
    pepsin_retropepsin_like; Cellular and retroviral pepsin-like aspartate proteases

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

    Range
    47726842..47734478
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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