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SCO2528 2-isopropylmalate synthase [ Streptomyces coelicolor A3(2) ]

Gene ID: 1097962, discontinued on 9-Sep-2022
  • This record was discontinued.
Gene symbol
SCO2528
Gene description
2-isopropylmalate synthase
Locus tag
SCO2528
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Streptomyces coelicolor A3(2) (serovar: A3(2))
Lineage
Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group
Also known as
leuA; SCC121.31c
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Genomic Sequence:
NC_003888.3

Go to nucleotide: Graphics FASTA GenBank

GeneRIFs: Gene References Into Functions

Miscellaneous features

  • Loc: c2726454-2726413 PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2
  • Loc: c2726979-2726194 Pfam match to entry PF00682 HMGL-like, , score 204.40, E-value 1.8e-57
  • Loc: c2727072-2727022 PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1
Names
2-isopropylmalate synthase
NP_733575.1
  • SCC121.31c, leuA, 2-ispoprylmalate synthase (EC 4.1.3.12), len: 499 aa; identical to C-terminal region of previously sequenced Streptomyces coelicolor 2-isopropylmalate synthase (EC 4.1.3.12) LeuA, 573 aa and highly similar to SW:LEU1_CORGL (EMBL:X70959) Corynebacterium glutamicum (Brevibacterium flavum) 2-isopropylmalate synthase (EC 4.1.3.12) (alpha-isopropylmalate synthase) (alpha-ipm synthetase) LeuA, 616 aa; fasta scores: opt: 1812 z-score: 2105.1 E(): 0; 55.1% identity in 506 aa overlap. Contains Pfam match to entry PF00682 HMGL-like and match to Prosite entry PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2
    SCC117.01c, leuA, 2-isopropylmalate synthase (EC 4.1.3.12) (fragment), len: > 113 aa. Previously sequenced and characterised Streptomyces coelicolor TR:O31046(EMBL:AF026444) (573 aa). Contains a Prosite hit to PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. Overlaps and extends into CDS SCC121.31c on the adjoining cosmid.

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003888.3 Reference assembly

    Range
    2725480..2727201 complement
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_733575.1 2-isopropylmalate synthase [Streptomyces coelicolor A3(2)]

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O31046.2

Gene LinkOut

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