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ileS isoleucyl-tRNA synthetase [ Streptomyces coelicolor A3(2) ]

Gene ID: 1097510, discontinued on 9-Sep-2022
  • This record was discontinued.
Gene symbol
ileS
Gene description
isoleucyl-tRNA synthetase
Locus tag
SCO2076
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Streptomyces coelicolor A3(2) (serovar: A3(2))
Lineage
Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group
Also known as
SC4A10.09
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Genomic Sequence:
NC_003888.3

Go to nucleotide: Graphics FASTA GenBank

GeneRIFs: Gene References Into Functions

Miscellaneous features

  • Loc: 2227297-2229342 Pfam match to entry PF00133 tRNA-synt_1, tRNA synthetases class I (I, L, M and V), score 723.00, E-value 1.3e-213
Names
isoleucyl-tRNA synthetase
NP_626335.1
  • IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003888.3 Reference assembly

    Range
    2227237..2230380
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_626335.1 isoleucyl-tRNA synthetase [Streptomyces coelicolor A3(2)]

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9S2X5.1

Gene LinkOut

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