Format

Send to:

Choose Destination

UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI [ Homo sapiens (human) ]

Gene ID: 10975, updated on 1-Jun-2020

Summary

Official Symbol
UQCR11provided by HGNC
Official Full Name
ubiquinol-cytochrome c reductase, complex III subunit XIprovided by HGNC
Primary source
HGNC:HGNC:30862
See related
Ensembl:ENSG00000127540 MIM:609711
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
UQCR; QCR10; 0710008D09Rik
Summary
This gene encodes the smallest known component of the ubiquinol-cytochrome c reductase complex, which forms part of the mitochondrial respiratory chain. The encoded protein may function as a binding factor for the iron-sulfur protein in this complex. [provided by RefSeq, Oct 2009]
Expression
Ubiquitous expression in colon (RPKM 36.3), fat (RPKM 35.6) and 25 other tissues See more
Orthologs

Genomic context

See UQCR11 in Genome Data Viewer
Location:
19p13.3
Exon count:
3
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (1597169..1605462, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (1597154..1605483, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene RNA, 7SL, cytoplasmic 477, pseudogene Neighboring gene methyl-CpG binding domain protein 3 Neighboring gene RNA, U6 small nuclear 1223, pseudogene Neighboring gene transcription factor 3 Neighboring gene uncharacterized LOC101928543 Neighboring gene one cut homeobox 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
electron transfer activity TAS
Traceable Author Statement
more info
PubMed 
ubiquinol-cytochrome-c reductase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial inner membrane TAS
Traceable Author Statement
more info
 
respiratory chain IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
cytochrome b-c1 complex subunit 10
Names
complex III subunit 10
complex III subunit XI
ubiquinol-cytochrome c reductase complex 6.4 kDa protein
ubiquinol-cytochrome c reductase, 6.4kDa subunit

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_006830.4NP_006821.1  cytochrome b-c1 complex subunit 10

    See identical proteins and their annotated locations for NP_006821.1

    Status: REVIEWED

    Source sequence(s)
    AA807820, BC003594, DW465790
    Consensus CDS
    CCDS12073.1
    UniProtKB/Swiss-Prot
    O14957
    Related
    ENSP00000467262.1, ENST00000591899.8
    Conserved Domains (1) summary
    pfam08997
    Location:155
    UCR_6-4kD; Ubiquinol-cytochrome C reductase complex, 6.4kD protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    1597169..1605462 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center