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ADIRF adipogenesis regulatory factor [ Homo sapiens (human) ]

Gene ID: 10974, updated on 6-Sep-2022

Summary

Official Symbol
ADIRFprovided by HGNC
Official Full Name
adipogenesis regulatory factorprovided by HGNC
Primary source
HGNC:HGNC:24043
See related
Ensembl:ENSG00000148671 AllianceGenome:HGNC:24043
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AFRO; APM2; apM-2; C10orf116
Summary
APM2 gene is exclusively expressed in adipose tissue. Its function is currently unknown. [provided by RefSeq, Jul 2008]
Expression
Biased expression in fat (RPKM 830.0), prostate (RPKM 218.1) and 10 other tissues See more
Orthologs
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Genomic context

See ADIRF in Genome Data Viewer
Location:
10q23.2
Exon count:
3
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (86968482..86970915)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (87852191..87854624)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (88728239..88730672)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene multimerin 2 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:88713843-88714442 Neighboring gene synuclein gamma Neighboring gene ADIRF antisense RNA 1 Neighboring gene Sharpr-MPRA regulatory region 6517 Neighboring gene uncharacterized LOC124902474 Neighboring gene ArfGAP with GTPase domain, ankyrin repeat and PH domain 11 Neighboring gene BMS1 pseudogene 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 
located_in extracellular exosome HDA PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
adipogenesis regulatory factor
Names
adipogenesis factor rich in obesity
adipose most abundant gene transcript 2 protein
adipose specific 2
adipose-specific protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_006829.3NP_006820.1  adipogenesis regulatory factor

    See identical proteins and their annotated locations for NP_006820.1

    Status: VALIDATED

    Source sequence(s)
    AI401530, AL136982, BM789611, BM850559, CD722742
    Consensus CDS
    CCDS7381.1
    UniProtKB/Swiss-Prot
    Q15847
    UniProtKB/TrEMBL
    Q5TBU5
    Related
    ENSP00000361083.3, ENST00000372013.8

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    86968482..86970915
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    87852191..87854624
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)