U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SCO1489 DNA-binding protein [ Streptomyces coelicolor A3(2) ]

Gene ID: 1096915, discontinued on 9-Sep-2022
  • This record was discontinued.
Gene symbol
SCO1489
Gene description
DNA-binding protein
Locus tag
SCO1489
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Streptomyces coelicolor A3(2) (serovar: A3(2))
Lineage
Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group
Also known as
bldD; SC9C5.13
NEW
Try the new Gene table
Try the new Transcript table
Genomic Sequence:
NC_003888.3

Go to nucleotide: Graphics FASTA GenBank

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A small elongated groove with conserved hydrophobic patches surrounded by charged residues suggests that the BldD-C-terminal domain could be involved in protein-protein interactions.
    Title: The C-terminal domain of the transcriptional regulator BldD from Streptomyces coelicolor A3(2) constitutes a novel fold of winged-helix domains.
  2. BldD acts as a repressor of key developmental genes during vegetative growth.
    Title: Genes essential for morphological development and antibiotic production in Streptomyces coelicolor are targets of BldD during vegetative growth.
  3. Results describe the crystal structure of the DNA-binding domain of BldD, and show that the Tyr62Cys mutation can destabilize BldD structure by disrupting the hydrophobic core.
    Title: Crystal structure of the DNA-binding domain of BldD, a central regulator of aerial mycelium formation in Streptomyces coelicolor A3(2).
  4. X-ray crystallographic analysis of the DNA-binding domain of BldD
    Title: Crystallization and preliminary X-ray crystallographic analysis of the DNA-binding domain of BldD from Streptomyces coelicolor A3(2).
  5. blocks sporulation prior to sporulation-specific septation but permits the formation of aerial hyphae
    Title: Critical residues and novel effects of overexpression of the Streptomyces coelicolor developmental protein BldB: evidence for a critical interacting partner.
Submit: New GeneRIF Correction

Miscellaneous features

  • Loc: 1592417-1592587 Pfam match to entry PF01381 HTH_3, Helix-turn-helix, score 47.10, E-value 3.9e-10
Names
DNA-binding protein
NP_625769.1
  • SC9C5.13, bldD, DNA-binding protein, len: 167 aa; identical to previously sequenced TR:O52732 (EMBL:AF045549) Streptomyces coelicolor DNA binding protein BldD, 167 aa. Contains Pfam match to entry PF01381 HTH_3, Helix-turn-helix

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003888.3 Reference assembly

    Range
    1592381..1592884
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_625769.1 DNA-binding protein [Streptomyces coelicolor A3(2)]

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.