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ribH 6,7-dimethyl-8-ribityllumazine synthase [ Streptomyces coelicolor A3(2) ]

Gene ID: 1096866, discontinued on 9-Sep-2022
  • This record was discontinued.
Gene symbol
ribH
Gene description
6,7-dimethyl-8-ribityllumazine synthase
Locus tag
SCO1440
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Streptomyces coelicolor A3(2) (serovar: A3(2))
Lineage
Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group
Also known as
SC6D7A.03c
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Genomic Sequence:
NC_003888.3

Miscellaneous features

  • Loc: c1536535-1536107 Pfam match to entry PF00885 DMRL_synthase, 6,7-dimethyl-8-ribityllumazine synthase, score 229.70, E-value 4.3e-65
Names
6,7-dimethyl-8-ribityllumazine synthase
NP_625721.1
  • RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003888.3 Reference assembly

    Range
    1536089..1536574 complement
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_625721.1 6,7-dimethyl-8-ribityllumazine synthase [Streptomyces coelicolor A3(2)]

    Status: REVIEWED