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Hoxc11 homeobox C11 [ Mus musculus (house mouse) ]

Gene ID: 109663, updated on 26-Sep-2022

Summary

Official Symbol
Hoxc11provided by MGI
Official Full Name
homeobox C11provided by MGI
Primary source
MGI:MGI:96193
See related
Ensembl:ENSMUSG00000001656 AllianceGenome:MGI:96193
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Hox-3.7
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including embryonic morphogenesis; organ induction; and regionalization. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including embryo mesenchyme; genitourinary system; hindlimb bud; limb; and nervous system. Orthologous to human HOXC11 (homeobox C11). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in limb E14.5 (RPKM 2.4), bladder adult (RPKM 1.2) and 3 other tissues See more
Orthologs
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Genomic context

See Hoxc11 in Genome Data Viewer
Location:
15 F3; 15 58.02 cM
Exon count:
2
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (102862961..102865136)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (102954526..102956701)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene homeobox C12 Neighboring gene HOX transcript antisense RNA (non-protein coding) Neighboring gene VISTA enhancer mm1417 Neighboring gene homeobox C10

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
homeobox protein Hox-C11
Names
homeo box C11
homeobox protein Hox-3.7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024842.1NP_001020013.1  homeobox protein Hox-C11

    See identical proteins and their annotated locations for NP_001020013.1

    Status: PROVISIONAL

    Source sequence(s)
    AC160979
    Consensus CDS
    CCDS27892.1
    UniProtKB/Swiss-Prot
    B9EI74, P31313
    UniProtKB/TrEMBL
    A0A6P5R7X5
    Related
    ENSMUSP00000001701.4, ENSMUST00000001701.4
    Conserved Domains (2) summary
    pfam00046
    Location:235289
    Homeobox; Homeobox domain
    pfam12045
    Location:42178
    DUF3528; Protein of unknown function (DUF3528)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    102862961..102865136
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)