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PAK4 p21 (RAC1) activated kinase 4 [ Hipposideros armiger (great roundleaf bat) ]

Gene ID: 109395380, updated on 8-Apr-2017

Summary

Gene symbol
PAK4
Gene description
p21 (RAC1) activated kinase 4
Gene type
protein coding
RefSeq status
MODEL
Organism
Hipposideros armiger
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Hipposideridae; Hipposideros
Orthologs

Genomic context

See PAK4 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
16
Annotation release Status Assembly Chr Location
100 current ASM189008v1 (GCF_001890085.1) Unplaced Scaffold NW_017731816.1 (353764..411384, complement)

NW_017731816.1Genomic Context describing neighboring genes Neighboring gene interferon lambda-3-like Neighboring gene non-specific cytotoxic cell receptor protein 1 homolog (zebrafish) Neighboring gene syncollin Neighboring gene 39S ribosomal protein L35, mitochondrial-like Neighboring gene acid phosphatase 7, tartrate resistant (putative) Neighboring gene F-box only protein 27-like

Genomic regions, transcripts, and products

Genomic Sequence:
NW_017731816.1 Unplaced Scaffold Reference ASM189008v1 Primary Assembly

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

  • Axon guidance, organism-specific biosystem (from KEGG)
    Axon guidance, organism-specific biosystemAxon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are...
  • Axon guidance, conserved biosystem (from KEGG)
    Axon guidance, conserved biosystemAxon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are...
  • ErbB signaling pathway, organism-specific biosystem (from KEGG)
    ErbB signaling pathway, organism-specific biosystemThe ErbB family of receptor tyrosine kinases (RTKs) couples binding of extracellular growth factor ligands to intracellular signaling pathways regulating diverse biologic responses, including prolife...
  • ErbB signaling pathway, conserved biosystem (from KEGG)
    ErbB signaling pathway, conserved biosystemThe ErbB family of receptor tyrosine kinases (RTKs) couples binding of extracellular growth factor ligands to intracellular signaling pathways regulating diverse biologic responses, including prolife...
  • Focal adhesion, organism-specific biosystem (from KEGG)
    Focal adhesion, organism-specific biosystemCell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the...
  • Focal adhesion, conserved biosystem (from KEGG)
    Focal adhesion, conserved biosystemCell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the...
  • MicroRNAs in cancer, organism-specific biosystem (from KEGG)
    MicroRNAs in cancer, organism-specific biosystemMicroRNA (miRNA) is a cluster of small non-encoding RNA molecules of 21 - 23 nucleotides in length, which controls gene expression post-transcriptionally either via the degradation of target mRNAs or...
  • MicroRNAs in cancer, conserved biosystem (from KEGG)
    MicroRNAs in cancer, conserved biosystemMicroRNA (miRNA) is a cluster of small non-encoding RNA molecules of 21 - 23 nucleotides in length, which controls gene expression post-transcriptionally either via the degradation of target mRNAs or...
  • Ras signaling pathway, organism-specific biosystem (from KEGG)
    Ras signaling pathway, organism-specific biosystemThe Ras proteins are GTPases that function as molecular switches for signaling pathways regulating cell proliferation, survival, growth, migration, differentiation or cytoskeletal dynamism. Ras prote...
  • Regulation of actin cytoskeleton, organism-specific biosystem (from KEGG)
    Regulation of actin cytoskeleton, organism-specific biosystem
    Regulation of actin cytoskeleton
  • Regulation of actin cytoskeleton, conserved biosystem (from KEGG)
    Regulation of actin cytoskeleton, conserved biosystem
    Regulation of actin cytoskeleton
  • Renal cell carcinoma, organism-specific biosystem (from KEGG)
    Renal cell carcinoma, organism-specific biosystemRenal cell cancer (RCC) accounts for ~3% of human malignancies and its incidence appears to be rising. Although most cases of RCC seem to occur sporadically, an inherited predisposition to renal canc...
  • Renal cell carcinoma, conserved biosystem (from KEGG)
    Renal cell carcinoma, conserved biosystemRenal cell cancer (RCC) accounts for ~3% of human malignancies and its incidence appears to be rising. Although most cases of RCC seem to occur sporadically, an inherited predisposition to renal canc...
  • T cell receptor signaling pathway, organism-specific biosystem (from KEGG)
    T cell receptor signaling pathway, organism-specific biosystemActivation of T lymphocytes is a key event for an efficient response of the immune system. It requires the involvement of the T-cell receptor (TCR) as well as costimulatory molecules such as CD28. En...
  • T cell receptor signaling pathway, conserved biosystem (from KEGG)
    T cell receptor signaling pathway, conserved biosystemActivation of T lymphocytes is a key event for an efficient response of the immune system. It requires the involvement of the T-cell receptor (TCR) as well as costimulatory molecules such as CD28. En...

General protein information

Preferred Names
serine/threonine-protein kinase PAK 4

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Hipposideros armiger Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM189008v1 Primary Assembly

Genomic

  1. NW_017731816.1 Reference ASM189008v1 Primary Assembly

    Range
    353764..411384 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019666312.1XP_019521857.1  serine/threonine-protein kinase PAK 4 isoform X1

  2. XM_019666313.1XP_019521858.1  serine/threonine-protein kinase PAK 4 isoform X1

  3. XM_019666320.1XP_019521865.1  serine/threonine-protein kinase PAK 4 isoform X2

  4. XM_019666317.1XP_019521862.1  serine/threonine-protein kinase PAK 4 isoform X1

  5. XM_019666315.1XP_019521860.1  serine/threonine-protein kinase PAK 4 isoform X1

  6. XM_019666316.1XP_019521861.1  serine/threonine-protein kinase PAK 4 isoform X1

  7. XM_019666314.1XP_019521859.1  serine/threonine-protein kinase PAK 4 isoform X1

  8. XM_019666318.1XP_019521863.1  serine/threonine-protein kinase PAK 4 isoform X1

  9. XM_019666319.1XP_019521864.1  serine/threonine-protein kinase PAK 4 isoform X1

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