U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tspan9 tetraspanin 9 [ Mus musculus (house mouse) ]

Gene ID: 109246, updated on 5-Jan-2023

Summary

Official Symbol
Tspan9provided by MGI
Official Full Name
tetraspanin 9provided by MGI
Primary source
MGI:MGI:1924558
See related
Ensembl:ENSMUSG00000030352 AllianceGenome:MGI:1924558
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tspan-9; 6720474K14Rik; 9430079M16Rik
Summary
Located in membrane. Is expressed in several structures, including central nervous system; diaphragm; gut; limb segment; and skeletal musculature. Orthologous to human TSPAN9 (tetraspanin 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in lung adult (RPKM 33.3), cerebellum adult (RPKM 22.3) and 27 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Tspan9 in Genome Data Viewer
Location:
6; 6 F3
Exon count:
12
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (127938359..128120541, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (127961396..128143578, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 38901 Neighboring gene predicted gene, 40401 Neighboring gene tetraspanin 11 Neighboring gene predicted gene, 38903 Neighboring gene predicted gene 15870 Neighboring gene predicted gene, 53341 Neighboring gene predicted gene, 34416 Neighboring gene predicted gene, 52879 Neighboring gene RIKEN cDNA 9330102E08 gene Neighboring gene Rho GTPase activating protein 20 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Endonuclease-mediated (3)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables signaling receptor binding ISO
Inferred from Sequence Orthology
more info
PubMed 
Component Evidence Code Pubs
located_in collagen-containing extracellular matrix ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in migrasome IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in tetraspanin-enriched microdomain ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
tetraspanin-9
Names
tetraspan NET-5

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001356301.2NP_001343230.1  tetraspanin-9 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2), as well as variants 1 and 3-5, encodes isoform b.
    Source sequence(s)
    AC135355, AC144778
    Consensus CDS
    CCDS20568.1
    UniProtKB/Swiss-Prot
    Q3TQQ0
    UniProtKB/TrEMBL
    A0A8C6HZ76
    Related
    ENSMUSP00000107796.2, ENSMUST00000112173.8
    Conserved Domains (2) summary
    cd03165
    Location:105202
    NET-5_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...
    pfam00335
    Location:9226
    Tetraspannin; Tetraspanin family
  2. NM_001379133.1NP_001366062.1  tetraspanin-9 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3), as well as variants 1, 2, 4, and 5, encodes isoform b.
    Source sequence(s)
    AC135355, AC144778
    UniProtKB/Swiss-Prot
    Q3TQQ0
    UniProtKB/TrEMBL
    A0A8C6HZ76
    Conserved Domains (2) summary
    cd03165
    Location:105202
    NET-5_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...
    pfam00335
    Location:9226
    Tetraspannin; Tetraspanin family
  3. NM_001379134.1NP_001366063.1  tetraspanin-9 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4), as well as variants 1-3 and 5, encodes isoform b.
    Source sequence(s)
    AC135355, AC144778
    UniProtKB/Swiss-Prot
    Q3TQQ0
    UniProtKB/TrEMBL
    A0A8C6HZ76
    Conserved Domains (2) summary
    cd03165
    Location:105202
    NET-5_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...
    pfam00335
    Location:9226
    Tetraspannin; Tetraspanin family
  4. NM_001379135.1NP_001366064.1  tetraspanin-9 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5), as well as variants 1-4, encodes isoform b.
    Source sequence(s)
    AC135355, AC144778
    UniProtKB/Swiss-Prot
    Q3TQQ0
    UniProtKB/TrEMBL
    A0A8C6HZ76
    Conserved Domains (2) summary
    cd03165
    Location:105202
    NET-5_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...
    pfam00335
    Location:9226
    Tetraspannin; Tetraspanin family
  5. NM_001379136.1NP_001366065.1  tetraspanin-9 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) represents the longest transcript and encodes the longer isoform (a).
    Source sequence(s)
    AC135355
    Conserved Domains (2) summary
    cd03165
    Location:196293
    NET-5_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...
    pfam00335
    Location:100317
    Tetraspannin; Tetraspanin family
  6. NM_175414.6NP_780623.1  tetraspanin-9 isoform b

    See identical proteins and their annotated locations for NP_780623.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1), as well as variants 2-5, encodes isoform b.
    Source sequence(s)
    AC135355, AC144778
    Consensus CDS
    CCDS20568.1
    UniProtKB/Swiss-Prot
    Q3TQQ0, Q8BJU2
    UniProtKB/TrEMBL
    A0A8C6HZ76
    Related
    ENSMUSP00000032503.6, ENSMUST00000032503.12
    Conserved Domains (2) summary
    cd03165
    Location:105202
    NET-5_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...
    pfam00335
    Location:9226
    Tetraspannin; Tetraspanin family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    127938359..128120541 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030255085.1XP_030110945.1  tetraspanin-9 isoform X1

    Conserved Domains (2) summary
    cd03165
    Location:142239
    NET-5_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...
    pfam00335
    Location:46263
    Tetraspannin; Tetraspanin family