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Atl3 atlastin GTPase 3 [ Mus musculus (house mouse) ]

Gene ID: 109168, updated on 12-Aug-2019

Summary

Official Symbol
Atl3provided by MGI
Official Full Name
atlastin GTPase 3provided by MGI
Primary source
MGI:MGI:1924270
See related
Ensembl:ENSMUSG00000024759
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AI465397; AW228836; 4633402C03Rik; 5730596K20Rik
Expression
Ubiquitous expression in testis adult (RPKM 31.9), bladder adult (RPKM 16.2) and 26 other tissues See more
Orthologs

Genomic context

See Atl3 in Genome Data Viewer
Location:
19; 19 A
Exon count:
14
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (7494015..7538609)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (7568530..7613099)

Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2700081O15 gene Neighboring gene reticulon 3 Neighboring gene uncharacterized LOC115489038 Neighboring gene phospholipase A and acyltransferase 3 Neighboring gene lectin, galactose binding, soluble 12

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Homology

Clone Names

  • MGC28761

Gene Ontology Provided by MGI

Function Evidence Code Pubs
GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
Golgi organization ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endoplasmic reticulum organization ISO
Inferred from Sequence Orthology
more info
 
positive regulation of endoplasmic reticulum tubular network organization ISO
Inferred from Sequence Orthology
more info
 
protein homooligomerization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein homooligomerization ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum tubular network ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum tubular network membrane ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163505.1NP_001156977.1  atlastin-3 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the shorter isoform (1).
    Source sequence(s)
    AC163276, AK077752, AK085735, AK147720, BP759756
    Consensus CDS
    CCDS50379.1
    UniProtKB/Swiss-Prot
    Q91YH5
    UniProtKB/TrEMBL
    E9PYT3
    Related
    ENSMUSP00000132619.1, ENSMUST00000170373.8
    Conserved Domains (2) summary
    cl20817
    Location:378427
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl21455
    Location:32300
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  2. NM_146091.4NP_666203.3  atlastin-3 isoform 2

    See identical proteins and their annotated locations for NP_666203.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is longer than isoform 1.
    Source sequence(s)
    AC163276, AK077752, AK085735, AK147720, BP759756, BY108453, CA318221
    Consensus CDS
    CCDS29527.1
    UniProtKB/Swiss-Prot
    Q91YH5
    Related
    ENSMUSP00000025668.7, ENSMUST00000025668.8
    Conserved Domains (2) summary
    cl20817
    Location:383432
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl21455
    Location:37305
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000085.6 Reference GRCm38.p6 C57BL/6J

    Range
    7494015..7538609
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006526604.4XP_006526667.1  atlastin-3 isoform X1

    Conserved Domains (2) summary
    cl20817
    Location:394443
    GBP_C; Guanylate-binding protein, C-terminal domain
    cl21455
    Location:48316
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
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