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Ints5 integrator complex subunit 5 [ Mus musculus (house mouse) ]

Gene ID: 109077, updated on 26-Sep-2022

Summary

Official Symbol
Ints5provided by MGI
Official Full Name
integrator complex subunit 5provided by MGI
Primary source
MGI:MGI:1923578
See related
Ensembl:ENSMUSG00000071652 AllianceGenome:MGI:1923578
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA1698; 1110055N21Rik
Summary
Predicted to be involved in snRNA 3'-end processing. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of integrator complex. Is expressed in forebrain ventricular layer and ganglionic eminence. Orthologous to human INTS5 (integrator complex subunit 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thymus adult (RPKM 17.6), ovary adult (RPKM 16.9) and 28 other tissues See more
Orthologs
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Genomic context

See Ints5 in Genome Data Viewer
Location:
19; 19 A
Exon count:
2
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (8870351..8875254)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (8892987..8897890)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 5730408K05 gene Neighboring gene LBH domain containing 1 Neighboring gene RIKEN cDNA 1810009A15 gene Neighboring gene microRNA 5136 Neighboring gene alpha glucosidase 2 alpha neutral subunit Neighboring gene predicted gene, 36629 Neighboring gene beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in snRNA 3'-end processing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in snRNA processing ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
part_of integrator complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of integrator complex ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
integrator complex subunit 5
Names
int5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_176843.3NP_789813.1  integrator complex subunit 5

    See identical proteins and their annotated locations for NP_789813.1

    Status: VALIDATED

    Source sequence(s)
    AC129217, AK168795, BY152900, BY546950
    Consensus CDS
    CCDS29556.1
    UniProtKB/Swiss-Prot
    Q3TM44, Q8CHT3
    Related
    ENSMUSP00000093968.6, ENSMUST00000096249.7
    Conserved Domains (2) summary
    pfam14837
    Location:29251
    INTS5_N; Integrator complex subunit 5 N-terminus
    pfam14838
    Location:289998
    INTS5_C; Integrator complex subunit 5 C-terminus

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    8870351..8875254
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)