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Stn1 STN1, CST complex subunit [ Mus musculus (house mouse) ]

Gene ID: 108689, updated on 3-Jun-2018
Official Symbol
Stn1provided by MGI
Official Full Name
STN1, CST complex subunitprovided by MGI
Primary source
MGI:MGI:1915581
See related
Ensembl:ENSMUSG00000042694 Vega:OTTMUSG00000043314
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AAF44; Obfc1; AAF-44; RPA-32; AI413458; 0610009H20Rik; 2310057J23Rik
Expression
Ubiquitous expression in limb E14.5 (RPKM 8.0), CNS E11.5 (RPKM 7.4) and 28 other tissues See more
Orthologs
See Stn1 in Genome Data Viewer
Location:
19; 19 C3
Exon count:
11
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 19 NC_000085.6 (47501048..47537121, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (47575538..47611510, complement)

Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene SH3 and PX domains 2A Neighboring gene predicted gene, 36885 Neighboring gene predicted gene, 41858 Neighboring gene predicted gene, 19557 Neighboring gene STE20-like kinase Neighboring gene predicted gene 16068 Neighboring gene collagen, type XVII, alpha 1

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Lung fibrosis, organism-specific biosystem (from WikiPathways)
    Lung fibrosis, organism-specific biosystem(Nanoparticle) induced lung fibrosis pathway. Under construction. Note! Mouse homologues for SERPINA1 and SFTPA2 are missing and the pathway currently contains the human equivalents. Other users are ...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
single-stranded DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
single-stranded telomeric DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
single-stranded telomeric DNA binding ISO
Inferred from Sequence Orthology
more info
 
telomeric DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
telomeric DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
telomeric DNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
negative regulation of telomere maintenance via telomerase ISO
Inferred from Sequence Orthology
more info
 
positive regulation of DNA replication IDA
Inferred from Direct Assay
more info
PubMed 
telomere capping IEA
Inferred from Electronic Annotation
more info
 
telomere maintenance ISO
Inferred from Sequence Orthology
more info
 
telomere maintenance via telomere lengthening ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
CST complex IDA
Inferred from Direct Assay
more info
PubMed 
CST complex ISO
Inferred from Sequence Orthology
more info
 
chromosome IEA
Inferred from Electronic Annotation
more info
 
chromosome, telomeric region IEA
Inferred from Electronic Annotation
more info
 
fibrillar center ISO
Inferred from Sequence Orthology
more info
 
intermediate filament cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
nuclear chromosome, telomeric region IDA
Inferred from Direct Assay
more info
PubMed 
nuclear chromosome, telomeric region ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
CST complex subunit STN1
Names
alpha accessory factor 44
alpha-accessory factor of 44 kDa
oligonucleotide/oligosaccharide-binding fold containing 1
oligonucleotide/oligosaccharide-binding fold-containing protein 1
replication protein A 32 kDa subunit
suppressor of cdc thirteen homolog

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175360.3NP_780569.1  CST complex subunit STN1

    See identical proteins and their annotated locations for NP_780569.1

    Status: VALIDATED

    Source sequence(s)
    AC125075, AK075574, AK164386
    Consensus CDS
    CCDS29892.1
    UniProtKB/Swiss-Prot
    Q8K2X3
    Related
    ENSMUSP00000040944.8, OTTMUSP00000063514, ENSMUST00000049369.15
    Conserved Domains (2) summary
    cd04483
    Location:65165
    hOBFC1_like; hOBFC1_like: A subfamily of OB folds similar to that found in human OB fold containing protein 1 (hOBFC1). Members of this group belong to the Replication protein A subunit 2 (RPA2) family of OB folds. RPA is a nuclear ssDNA binding protein (SSB) which ...
    pfam09170
    Location:167344
    STN1_2; CST, Suppressor of cdc thirteen homolog, complex subunit STN1

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000085.6 Reference GRCm38.p4 C57BL/6J

    Range
    47501048..47537121 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006526598.3XP_006526661.1  CST complex subunit STN1 isoform X1

    See identical proteins and their annotated locations for XP_006526661.1

    UniProtKB/TrEMBL
    Q3UXU8
    Related
    ENSMUSP00000138727.1, OTTMUSP00000063515, ENSMUST00000182808.7, OTTMUST00000113652
    Conserved Domains (2) summary
    cd04483
    Location:65165
    hOBFC1_like; hOBFC1_like: A subfamily of OB folds similar to that found in human OB fold containing protein 1 (hOBFC1). Members of this group belong to the Replication protein A subunit 2 (RPA2) family of OB folds. RPA is a nuclear ssDNA binding protein (SSB) which ...
    pfam09170
    Location:167326
    STN1_2; CST, Suppressor of cdc thirteen homolog, complex subunit STN1
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