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CD3EAP CD3e molecule associated protein [ Homo sapiens (human) ]

Gene ID: 10849, updated on 23-Nov-2017
Official Symbol
CD3EAPprovided by HGNC
Official Full Name
CD3e molecule associated proteinprovided by HGNC
Primary source
HGNC:HGNC:24219
See related
Ensembl:ENSG00000117877 MIM:107325; Vega:OTTHUMG00000182120
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ASE1; CAST; ASE-1; PAF49
Orthologs
Location:
19q13.32
Exon count:
3
Annotation release Status Assembly Chr Location
108 current GRCh38.p7 (GCF_000001405.33) 19 NC_000019.10 (45406129..45410766)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (45909467..45914024)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ribosomal protein S16 pseudogene 9 Neighboring gene kinesin light chain 3 Neighboring gene ERCC excision repair 2, TFIIH core complex helicase subunit Neighboring gene protein phosphatase 1 regulatory subunit 13 like Neighboring gene ERCC excision repair 1, endonuclease non-catalytic subunit Neighboring gene microRNA 6088 Neighboring gene FosB proto-oncogene, AP-1 transcription factor subunit

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC118851

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA-directed 5'-3' RNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 
RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
RNA polymerase I transcription factor complex TAS
Traceable Author Statement
more info
PubMed 
chromosome IEA
Inferred from Electronic Annotation
more info
 
cytosol IDA
Inferred from Direct Assay
more info
 
fibrillar center IDA
Inferred from Direct Assay
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
 
nucleolus TAS
Traceable Author Statement
more info
PubMed 
nucleoplasm TAS
Traceable Author Statement
more info
 
nucleus IDA
Inferred from Direct Assay
more info
 
Preferred Names
DNA-directed RNA polymerase I subunit RPA34
Names
CD3e antigen, epsilon polypeptide associated protein
CD3e molecule, epsilon associated protein
RNA polymerase I-associated factor PAF49
antisense to ERCC-1 protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001297590.1NP_001284519.1  DNA-directed RNA polymerase I subunit RPA34 isoform 1

    See identical proteins and their annotated locations for NP_001284519.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AF017633, BU166593, U86751
    Consensus CDS
    CCDS74397.1
    UniProtKB/Swiss-Prot
    O15446
    Related
    ENSP00000465099.1, OTTHUMP00000268421, ENST00000589804.1, OTTHUMT00000459540
    Conserved Domains (1) summary
    pfam08208
    Location:40180
    RNA_polI_A34; DNA-directed RNA polymerase I subunit RPA34.5
  2. NM_012099.1NP_036231.1  DNA-directed RNA polymerase I subunit RPA34 isoform 2

    See identical proteins and their annotated locations for NP_036231.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. It encodes isoform 2, which is shorter than isoform 1.
    Source sequence(s)
    U86751
    Consensus CDS
    CCDS12661.1
    UniProtKB/Swiss-Prot
    O15446
    Related
    ENSP00000310966.3, OTTHUMP00000268419, ENST00000309424.7, OTTHUMT00000459538
    Conserved Domains (1) summary
    pfam08208
    Location:38178
    RNA_polI_A34; DNA-directed RNA polymerase I subunit RPA34.5

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p7 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p7 Primary Assembly

    Range
    45406129..45410766
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017026180.1XP_016881669.1  DNA-directed RNA polymerase I subunit RPA34 isoform X1

  2. XM_017026181.1XP_016881670.1  DNA-directed RNA polymerase I subunit RPA34 isoform X1

Alternate CHM1_1.1

Genomic

  1. NC_018930.2 Alternate CHM1_1.1

    Range
    45912759..45917316
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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