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Grm3 glutamate receptor, metabotropic 3 [ Mus musculus (house mouse) ]

Gene ID: 108069, updated on 12-Aug-2019

Summary

Official Symbol
Grm3provided by MGI
Official Full Name
glutamate receptor, metabotropic 3provided by MGI
Primary source
MGI:MGI:1351340
See related
Ensembl:ENSMUSG00000003974
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mGlu3; Gprc1c; mGluR3; 0710001G23Rik
Expression
Biased expression in cortex adult (RPKM 11.5), frontal lobe adult (RPKM 9.3) and 4 other tissues See more
Orthologs

Genomic context

See Grm3 in Genome Data Viewer
Location:
5; 5 A1
Exon count:
6
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (9485236..9725352, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (9485236..9725352, complement)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 9330182L06 gene Neighboring gene protein phosphatase 1, regulatory (inhibitor) subunit 14B pseudogene Neighboring gene microRNA 879 Neighboring gene predicted gene, 23312 Neighboring gene predicted gene, 35139

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
calcium channel regulator activity IDA
Inferred from Direct Assay
more info
PubMed 
glutamate receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
group II metabotropic glutamate receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
group II metabotropic glutamate receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
group II metabotropic glutamate receptor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
G protein-coupled glutamate receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
cellular response to stress IDA
Inferred from Direct Assay
more info
PubMed 
modulation of chemical synaptic transmission ISO
Inferred from Sequence Orthology
more info
 
regulation of sensory perception of pain NAS
Non-traceable Author Statement
more info
PubMed 
regulation of synaptic transmission, glutamatergic IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
sensory perception of pain TAS
Traceable Author Statement
more info
PubMed 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
synaptic transmission, glutamatergic TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
astrocyte projection ISO
Inferred from Sequence Orthology
more info
 
axon IDA
Inferred from Direct Assay
more info
PubMed 
dendritic spine IDA
Inferred from Direct Assay
more info
PubMed 
glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of postsynaptic membrane IDA
Inferred from Direct Assay
more info
PubMed 
integral component of presynaptic membrane IDA
Inferred from Direct Assay
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
neuron projection IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
postsynaptic density IDA
Inferred from Direct Assay
more info
PubMed 
postsynaptic membrane IDA
Inferred from Direct Assay
more info
PubMed 
presynaptic active zone NAS
Non-traceable Author Statement
more info
PubMed 
presynaptic membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
metabotropic glutamate receptor 3
Names
G protein-coupled receptor, family C, group 1, member C

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_181850.2NP_862898.1  metabotropic glutamate receptor 3 precursor

    See identical proteins and their annotated locations for NP_862898.1

    Status: PROVISIONAL

    Source sequence(s)
    AC157555, AC162520
    Consensus CDS
    CCDS19090.1
    UniProtKB/Swiss-Prot
    Q9QYS2
    Related
    ENSMUSP00000004076.3, ENSMUST00000004076.4
    Conserved Domains (4) summary
    cd06375
    Location:37494
    PBP1_mGluR_groupII; Ligand binding domain of the group II metabotropic glutamate receptor
    pfam00003
    Location:588825
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    pfam01094
    Location:67469
    ANF_receptor; Receptor family ligand binding region
    pfam07562
    Location:506554
    NCD3G; Nine Cysteines Domain of family 3 GPCR

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000071.6 Reference GRCm38.p6 C57BL/6J

    Range
    9485236..9725352 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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